Detection and follow-up of cardiovascular disease and risk factors in the Southern Cone of Latin America: the CESCAS I study
IntroductionCardiovascular diseases (CVD) are increasing throughout the world and cause 16.7 million deaths each year, 80% of which occur in low and middle income countries. In Argentina, Chile and Uruguay, the available data on cardiovascular risk factors come predominantly from cross-sectional stu...
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| creator | Rubinstein, Adolfo Luis Irazola, Vilma Edith Poggio, Rosana Bazzano, Lydia Calandrelli, Matías Lanas Zanetti, Fernando Tomas Manfredi, Jose Anibal Olivera, Héctor Seron, Pamela Ponzo, Jacqueline He, Jiang |
| description | IntroductionCardiovascular diseases (CVD) are increasing throughout the world and cause 16.7 million deaths each year, 80% of which occur in low and middle income countries. In Argentina, Chile and Uruguay, the available data on cardiovascular risk factors come predominantly from cross-sectional studies that are principally based on self-report or studies conducted with small convenience samples. The CESCAS I study will generate reliable estimates of the prevalence and distribution of and secular trends in CVD and its risk factors in this region.Methods and analysisCESCAS I is an observational prospective cohort study with a multistage probabilistic sample of 8000 participants aged 35–74 years from four mid-sized cities representing the Southern Cone of Latin America: Bariloche and Marcos Paz in Argentina, Temuco in Chile and Pando-Barros Blancos in Uruguay. In the first phase, baseline data regarding exposure to risk factors and prevalence of CVD will be collected in two stages: (1) in homes and (2) in health centres. Information will be gathered on medical history, risk factors, lifestyles and health utilisation through specific questionnaires, physical measurements, an ECG and an overnight, fasting blood sample to measure levels of serum lipids, glucose and creatinine. In the second phase, annual follow-up data will be obtained on the incidence rate of CVD events and the association between exposure and events.Ethics and disseminationThe protocol has obtained formal ethics approval from institutional review boards in Argentina, Chile, Uruguay and the USA. The lack of follow-up studies has prevented Argentina, Chile and Uruguay from implementing risk factor stratification and management strategies at a population level. However, the CESCAS I study data will help the development of public health strategies based on primary care intervention, thus helping to improve cardiovascular health in this region. |
| doi_str_mv | 10.1136/bmjopen-2011-000126 |
| format | Article |
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In Argentina, Chile and Uruguay, the available data on cardiovascular risk factors come predominantly from cross-sectional studies that are principally based on self-report or studies conducted with small convenience samples. The CESCAS I study will generate reliable estimates of the prevalence and distribution of and secular trends in CVD and its risk factors in this region.Methods and analysisCESCAS I is an observational prospective cohort study with a multistage probabilistic sample of 8000 participants aged 35–74 years from four mid-sized cities representing the Southern Cone of Latin America: Bariloche and Marcos Paz in Argentina, Temuco in Chile and Pando-Barros Blancos in Uruguay. In the first phase, baseline data regarding exposure to risk factors and prevalence of CVD will be collected in two stages: (1) in homes and (2) in health centres. Information will be gathered on medical history, risk factors, lifestyles and health utilisation through specific questionnaires, physical measurements, an ECG and an overnight, fasting blood sample to measure levels of serum lipids, glucose and creatinine. In the second phase, annual follow-up data will be obtained on the incidence rate of CVD events and the association between exposure and events.Ethics and disseminationThe protocol has obtained formal ethics approval from institutional review boards in Argentina, Chile, Uruguay and the USA. The lack of follow-up studies has prevented Argentina, Chile and Uruguay from implementing risk factor stratification and management strategies at a population level. However, the CESCAS I study data will help the development of public health strategies based on primary care intervention, thus helping to improve cardiovascular health in this region.</description><identifier>ISSN: 2044-6055</identifier><identifier>EISSN: 2044-6055</identifier><identifier>DOI: 10.1136/bmjopen-2011-000126</identifier><identifier>PMID: 22021769</identifier><language>eng</language><publisher>England: British Medical Journal Publishing Group</publisher><subject>Age ; Alcohol ; Blood pressure ; Cancer ; Cardiovascular disease ; Data collection ; Diabetes ; Epidemiology ; Households ; Hypertension ; Industrialized nations ; Population ; Protocol ; Questionnaires ; Risk factors ; Smoking ; Tobacco ; Trends ; Womens health</subject><ispartof>BMJ open, 2011-01, Vol.1 (1), p.e000126-e000126</ispartof><rights>2011, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.</rights><rights>2011 2011, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non commercial and is otherwise in compliance with the license. See: http://creativecommons.org/licenses/by-nc/2.0/ and http://creativecommons.org/licenses/by-nc/2.0/legalcode . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2011, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions. 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b511t-e38e8b4c7fb4f513784815ff6a8aa7abb26105bb4b64d99515a7c5965c05e2fc3</citedby><cites>FETCH-LOGICAL-b511t-e38e8b4c7fb4f513784815ff6a8aa7abb26105bb4b64d99515a7c5965c05e2fc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://bmjopen.bmj.com/content/1/1/e000126.full.pdf$$EPDF$$P50$$Gbmj$$Hfree_for_read</linktopdf><linktohtml>$$Uhttp://bmjopen.bmj.com/content/1/1/e000126.full$$EHTML$$P50$$Gbmj$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27549,27550,27924,27925,53791,53793,55350,77601,77632,77660,77686</link.rule.ids><linktorsrc>$$Uhttps://bmjopen.bmj.com/content/early/2011/05/26/bmjopen-2011-000126.full$$EView_record_in_BMJ_Publishing_Group_Ltd$$FView_record_in_$$GBMJ_Publishing_Group_Ltd</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22021769$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rubinstein, Adolfo Luis</creatorcontrib><creatorcontrib>Irazola, Vilma Edith</creatorcontrib><creatorcontrib>Poggio, Rosana</creatorcontrib><creatorcontrib>Bazzano, Lydia</creatorcontrib><creatorcontrib>Calandrelli, Matías</creatorcontrib><creatorcontrib>Lanas Zanetti, Fernando Tomas</creatorcontrib><creatorcontrib>Manfredi, Jose Anibal</creatorcontrib><creatorcontrib>Olivera, Héctor</creatorcontrib><creatorcontrib>Seron, Pamela</creatorcontrib><creatorcontrib>Ponzo, Jacqueline</creatorcontrib><creatorcontrib>He, Jiang</creatorcontrib><title>Detection and follow-up of cardiovascular disease and risk factors in the Southern Cone of Latin America: the CESCAS I study</title><title>BMJ open</title><addtitle>BMJ Open</addtitle><addtitle>BMJ Open</addtitle><description>IntroductionCardiovascular diseases (CVD) are increasing throughout the world and cause 16.7 million deaths each year, 80% of which occur in low and middle income countries. In Argentina, Chile and Uruguay, the available data on cardiovascular risk factors come predominantly from cross-sectional studies that are principally based on self-report or studies conducted with small convenience samples. The CESCAS I study will generate reliable estimates of the prevalence and distribution of and secular trends in CVD and its risk factors in this region.Methods and analysisCESCAS I is an observational prospective cohort study with a multistage probabilistic sample of 8000 participants aged 35–74 years from four mid-sized cities representing the Southern Cone of Latin America: Bariloche and Marcos Paz in Argentina, Temuco in Chile and Pando-Barros Blancos in Uruguay. In the first phase, baseline data regarding exposure to risk factors and prevalence of CVD will be collected in two stages: (1) in homes and (2) in health centres. Information will be gathered on medical history, risk factors, lifestyles and health utilisation through specific questionnaires, physical measurements, an ECG and an overnight, fasting blood sample to measure levels of serum lipids, glucose and creatinine. In the second phase, annual follow-up data will be obtained on the incidence rate of CVD events and the association between exposure and events.Ethics and disseminationThe protocol has obtained formal ethics approval from institutional review boards in Argentina, Chile, Uruguay and the USA. The lack of follow-up studies has prevented Argentina, Chile and Uruguay from implementing risk factor stratification and management strategies at a population level. However, the CESCAS I study data will help the development of public health strategies based on primary care intervention, thus helping to improve cardiovascular health in this region.</description><subject>Age</subject><subject>Alcohol</subject><subject>Blood pressure</subject><subject>Cancer</subject><subject>Cardiovascular disease</subject><subject>Data collection</subject><subject>Diabetes</subject><subject>Epidemiology</subject><subject>Households</subject><subject>Hypertension</subject><subject>Industrialized nations</subject><subject>Population</subject><subject>Protocol</subject><subject>Questionnaires</subject><subject>Risk factors</subject><subject>Smoking</subject><subject>Tobacco</subject><subject>Trends</subject><subject>Womens health</subject><issn>2044-6055</issn><issn>2044-6055</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>ACMMV</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkUFrFDEYhgdR2lL7CwoS8OBp2iSTZCYehGVatbDgYfUckkxis84ka5JpKfTHm-2ubfUgnr5Anufl-3ir6hTBM4Qadq6mddgYX2OIUA0hRJi9qI4wJKRmkNKXz96H1UlK68JAQjml-KA6xBhi1DJ-VN1fmGx0dsED6QdgwziG23regGCBlnFw4UYmPY8ygsElI5N54KJLP4CVOoeYgPMgXxuwCnMZ0YM-eLP1lzKXr8VkotPy_QPTX676xQpcgZTn4e519crKMZmT_Tyuvn28_Np_rpdfPl31i2WtKEK5Nk1nOkV0axWxFDVtRzpErWWyk7KVSmGGIFWKKEYGzimistWUM6ohNdjq5rj6sMvdzGoygzY-RzmKTXSTjHciSCf-_PHuWnwPN6JBHJGmKwHv9gEx_JxNymJySZtxlN6EOQkOIWsY56SQb_8i12GOvlwnUNs1hHNMWaGaHaVjSCka-7gLgmLbr9j3K7b9il2_xXrz_IxH53ebBTjbAcX-z8TzJ-Fp0X8YvwBt9MDW</recordid><startdate>20110101</startdate><enddate>20110101</enddate><creator>Rubinstein, Adolfo Luis</creator><creator>Irazola, Vilma Edith</creator><creator>Poggio, Rosana</creator><creator>Bazzano, Lydia</creator><creator>Calandrelli, Matías</creator><creator>Lanas Zanetti, Fernando Tomas</creator><creator>Manfredi, Jose Anibal</creator><creator>Olivera, Héctor</creator><creator>Seron, Pamela</creator><creator>Ponzo, Jacqueline</creator><creator>He, Jiang</creator><general>British Medical Journal Publishing Group</general><general>BMJ Publishing Group LTD</general><general>BMJ Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20110101</creationdate><title>Detection and follow-up of cardiovascular disease and risk factors in the Southern Cone of Latin America: the CESCAS I study</title><author>Rubinstein, Adolfo Luis ; Irazola, Vilma Edith ; Poggio, Rosana ; Bazzano, Lydia ; Calandrelli, Matías ; Lanas Zanetti, Fernando Tomas ; Manfredi, Jose Anibal ; Olivera, Héctor ; Seron, Pamela ; Ponzo, Jacqueline ; He, Jiang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b511t-e38e8b4c7fb4f513784815ff6a8aa7abb26105bb4b64d99515a7c5965c05e2fc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Age</topic><topic>Alcohol</topic><topic>Blood pressure</topic><topic>Cancer</topic><topic>Cardiovascular disease</topic><topic>Data collection</topic><topic>Diabetes</topic><topic>Epidemiology</topic><topic>Households</topic><topic>Hypertension</topic><topic>Industrialized nations</topic><topic>Population</topic><topic>Protocol</topic><topic>Questionnaires</topic><topic>Risk factors</topic><topic>Smoking</topic><topic>Tobacco</topic><topic>Trends</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rubinstein, Adolfo Luis</creatorcontrib><creatorcontrib>Irazola, Vilma Edith</creatorcontrib><creatorcontrib>Poggio, Rosana</creatorcontrib><creatorcontrib>Bazzano, Lydia</creatorcontrib><creatorcontrib>Calandrelli, Matías</creatorcontrib><creatorcontrib>Lanas Zanetti, Fernando Tomas</creatorcontrib><creatorcontrib>Manfredi, Jose Anibal</creatorcontrib><creatorcontrib>Olivera, Héctor</creatorcontrib><creatorcontrib>Seron, Pamela</creatorcontrib><creatorcontrib>Ponzo, Jacqueline</creatorcontrib><creatorcontrib>He, Jiang</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database (ProQuest)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ open</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Rubinstein, Adolfo Luis</au><au>Irazola, Vilma Edith</au><au>Poggio, Rosana</au><au>Bazzano, Lydia</au><au>Calandrelli, Matías</au><au>Lanas Zanetti, Fernando Tomas</au><au>Manfredi, Jose Anibal</au><au>Olivera, Héctor</au><au>Seron, Pamela</au><au>Ponzo, Jacqueline</au><au>He, Jiang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Detection and follow-up of cardiovascular disease and risk factors in the Southern Cone of Latin America: the CESCAS I study</atitle><jtitle>BMJ open</jtitle><stitle>BMJ Open</stitle><addtitle>BMJ Open</addtitle><date>2011-01-01</date><risdate>2011</risdate><volume>1</volume><issue>1</issue><spage>e000126</spage><epage>e000126</epage><pages>e000126-e000126</pages><issn>2044-6055</issn><eissn>2044-6055</eissn><abstract>IntroductionCardiovascular diseases (CVD) are increasing throughout the world and cause 16.7 million deaths each year, 80% of which occur in low and middle income countries. In Argentina, Chile and Uruguay, the available data on cardiovascular risk factors come predominantly from cross-sectional studies that are principally based on self-report or studies conducted with small convenience samples. The CESCAS I study will generate reliable estimates of the prevalence and distribution of and secular trends in CVD and its risk factors in this region.Methods and analysisCESCAS I is an observational prospective cohort study with a multistage probabilistic sample of 8000 participants aged 35–74 years from four mid-sized cities representing the Southern Cone of Latin America: Bariloche and Marcos Paz in Argentina, Temuco in Chile and Pando-Barros Blancos in Uruguay. In the first phase, baseline data regarding exposure to risk factors and prevalence of CVD will be collected in two stages: (1) in homes and (2) in health centres. Information will be gathered on medical history, risk factors, lifestyles and health utilisation through specific questionnaires, physical measurements, an ECG and an overnight, fasting blood sample to measure levels of serum lipids, glucose and creatinine. In the second phase, annual follow-up data will be obtained on the incidence rate of CVD events and the association between exposure and events.Ethics and disseminationThe protocol has obtained formal ethics approval from institutional review boards in Argentina, Chile, Uruguay and the USA. The lack of follow-up studies has prevented Argentina, Chile and Uruguay from implementing risk factor stratification and management strategies at a population level. However, the CESCAS I study data will help the development of public health strategies based on primary care intervention, thus helping to improve cardiovascular health in this region.</abstract><cop>England</cop><pub>British Medical Journal Publishing Group</pub><pmid>22021769</pmid><doi>10.1136/bmjopen-2011-000126</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Age Alcohol Blood pressure Cancer Cardiovascular disease Data collection Diabetes Epidemiology Households Hypertension Industrialized nations Population Protocol Questionnaires Risk factors Smoking Tobacco Trends Womens health |
| title | Detection and follow-up of cardiovascular disease and risk factors in the Southern Cone of Latin America: the CESCAS I study |
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