MAGUKs, Synaptic Development, and Synaptic Plasticity

MAGUKs are proteins that act as key scaffolds in surface complexes containing receptors, adhesion proteins, and various signaling molecules. These complexes evolved prior to the appearance of multicellular animals and play key roles in cell-cell intercommunication. A major example of this is the neu...

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Veröffentlicht in:	The Neuroscientist (Baltimore, Md.) Md.), 2011-10, Vol.17 (5), p.493-512
Hauptverfasser:	Zheng, Chan-Ying, Seabold, Gail K., Horak, Martin, Petralia, Ronald S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - chemistry Adaptor Proteins, Signal Transducing - metabolism Animals Cell Adhesion Molecules, Neuronal - chemistry Cell Adhesion Molecules, Neuronal - metabolism Disks Large Homolog 4 Protein Guanylate Kinases - chemistry Guanylate Kinases - metabolism Humans Intracellular Signaling Peptides and Proteins - chemistry Intracellular Signaling Peptides and Proteins - metabolism Membrane Proteins - chemistry Membrane Proteins - metabolism Neuronal Plasticity - physiology Nuclear Proteins - chemistry Nuclear Proteins - metabolism Synapses - chemistry Synapses - metabolism Transcription Factors - chemistry Transcription Factors - metabolism
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