The Dystrophin-Glycoprotein Complex in the Prevention of Muscle Damage

Muscular dystrophies are genetically diverse but share common phenotypic features of muscle weakness, degeneration, and progressive decline in muscle function. Previous work has focused on understanding how disruptions in the dystrophin-glycoprotein complex result in muscular dystrophy, supporting a...

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Veröffentlicht in:	BioMed research international 2011-01, Vol.2011 (2011), p.1-13
Hauptverfasser:	Gumerson, Jessica D., Michele, Daniel E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dystrophin - metabolism Glycoproteins - metabolism Humans Laminin - metabolism Mice Mice, Inbred mdx - metabolism Muscle Contraction - physiology Muscle, Skeletal - metabolism Muscular Dystrophies - physiopathology Review Sarcolemma - metabolism Signal Transduction Stress, Mechanical
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