Methylphenidate increases cigarette smoking in participants with ADHD
Rationale Methylphenidate (Ritalin®) is commonly prescribed for behavioral problems associated with attention deficit/hyperactivity disorder (ADHD). The results of previous studies suggest that methylphenidate increases cigarette smoking in participants without psychiatric diagnoses. Whether methylp...
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| Veröffentlicht in: | Psychopharmacologia 2011-11, Vol.218 (2), p.381-390 |
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| creator | Vansickel, Andrea R. Stoops, William W. Glaser, Paul E. A. Poole, Megan M. Rush, Craig R. |
| description | Rationale
Methylphenidate (Ritalin®) is commonly prescribed for behavioral problems associated with attention deficit/hyperactivity disorder (ADHD). The results of previous studies suggest that methylphenidate increases cigarette smoking in participants without psychiatric diagnoses. Whether methylphenidate increases cigarette smoking in participants diagnosed with ADHD is unknown.
Objective
In this within-subjects, repeated measures experiment, the acute effects of a range of doses of methylphenidate (10, 20, and 40 mg) and placebo were assessed in nine cigarette smokers who were not attempting to quit and met diagnostic criteria for ADHD but no other Axis I psychiatric disorders other than nicotine dependence.
Methods
Each dose of methylphenidate was tested once while placebo was tested twice. One hour after ingesting drug, participants were allowed to smoke ad libitum for 4 h. Measures of smoking included total cigarettes smoked, total puffs, and carbon monoxide levels. Snacks and decaffeinated drinks were available ad libitum; caloric intake during the 4-h smoking session was calculated.
Results
Methylphenidate increased the total number of cigarettes smoked, total number of puffs, and carbon monoxide levels. Methylphenidate decreased the number of food items consumed and caloric intake.
Conclusions
The results of this experiment suggest that acutely administered methylphenidate increases cigarette smoking in participants with ADHD, which is concordant with findings from previous studies that tested healthy young adults. These data indicate that clinicians may need to consider non-stimulant options or counsel their patients before starting methylphenidate when managing ADHD-diagnosed individuals who smoke. |
| doi_str_mv | 10.1007/s00213-011-2328-y |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3189423</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A354577995</galeid><sourcerecordid>A354577995</sourcerecordid><originalsourceid>FETCH-LOGICAL-c597t-c0ba23b488a4cf3f50643735dfe2f2a3945098400c94fcbc1c1072c0920c17253</originalsourceid><addsrcrecordid>eNp1kU1v1DAQhi0EokvhB3BBEQhxShl_beIL0qotFKmIC5wt76yddUmcYGdb7b_HUZaWotY-WJp55p0Zv4S8pnBCAaqPCYBRXgKlJeOsLvdPyIIKzkoGFXtKFgCcl5zK-oi8SOkK8hG1eE6OGJUKWC0W5PybHbf7dtja4DdmtIUPGK1JNhXoGxPtmGOp63_50ORcMZg4evSDCWMqbvy4LVZnF2cvyTNn2mRfHd5j8vPz-Y_Ti_Ly-5evp6vLEqWqxhJhbRhfi7o2Ah13EpaCV1xunGWOGa6EBFULAFTC4Rop0rwIgmKAtGKSH5NPs-6wW3d2gzaM0bR6iL4zca974_X9TPBb3fTXmtNaCcazwIeDQOx_72wadecT2rY1wfa7pBVbKshziEy-_Y-86ncx5O10rRTPwyyrDL2boca0Vvvg-twVJ0m94lLIqlJqmvrkASrfje089sE6n-P3CuhcgLFPKVp3uyEFPTmvZ-d1dl5Pzut9rnnz79fcVvy1OgPvD4BJaFoXTUCf7jixVFxWE8dmLuVUaGy8W_zx7n8AH7jEpA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>899325367</pqid></control><display><type>article</type><title>Methylphenidate increases cigarette smoking in participants with ADHD</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>Vansickel, Andrea R. ; Stoops, William W. ; Glaser, Paul E. A. ; Poole, Megan M. ; Rush, Craig R.</creator><creatorcontrib>Vansickel, Andrea R. ; Stoops, William W. ; Glaser, Paul E. A. ; Poole, Megan M. ; Rush, Craig R.</creatorcontrib><description>Rationale
Methylphenidate (Ritalin®) is commonly prescribed for behavioral problems associated with attention deficit/hyperactivity disorder (ADHD). The results of previous studies suggest that methylphenidate increases cigarette smoking in participants without psychiatric diagnoses. Whether methylphenidate increases cigarette smoking in participants diagnosed with ADHD is unknown.
Objective
In this within-subjects, repeated measures experiment, the acute effects of a range of doses of methylphenidate (10, 20, and 40 mg) and placebo were assessed in nine cigarette smokers who were not attempting to quit and met diagnostic criteria for ADHD but no other Axis I psychiatric disorders other than nicotine dependence.
Methods
Each dose of methylphenidate was tested once while placebo was tested twice. One hour after ingesting drug, participants were allowed to smoke ad libitum for 4 h. Measures of smoking included total cigarettes smoked, total puffs, and carbon monoxide levels. Snacks and decaffeinated drinks were available ad libitum; caloric intake during the 4-h smoking session was calculated.
Results
Methylphenidate increased the total number of cigarettes smoked, total number of puffs, and carbon monoxide levels. Methylphenidate decreased the number of food items consumed and caloric intake.
Conclusions
The results of this experiment suggest that acutely administered methylphenidate increases cigarette smoking in participants with ADHD, which is concordant with findings from previous studies that tested healthy young adults. These data indicate that clinicians may need to consider non-stimulant options or counsel their patients before starting methylphenidate when managing ADHD-diagnosed individuals who smoke.</description><identifier>ISSN: 0033-3158</identifier><identifier>EISSN: 1432-2072</identifier><identifier>DOI: 10.1007/s00213-011-2328-y</identifier><identifier>PMID: 21590284</identifier><identifier>CODEN: PSYPAG</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Acute effects ; Addictive behaviors ; Adult ; Adult and adolescent clinical studies ; Attention Deficit Disorder with Hyperactivity - drug therapy ; Attention deficit hyperactivity disorder ; Beverages ; Biological and medical sciences ; Biomedical and Life Sciences ; Biomedicine ; Carbon monoxide ; Carbon Monoxide - analysis ; Central Nervous System Stimulants - administration & dosage ; Central Nervous System Stimulants - pharmacology ; Cigarette smoking ; Cigarettes ; Data processing ; Dose-Response Relationship, Drug ; Double-Blind Method ; Drug dependence ; Drug therapy ; Drugs ; Eating - drug effects ; Energy Intake - drug effects ; Female ; Food ; Health aspects ; Humans ; Hyperactivity ; Male ; Medical sciences ; Mental disorders ; Methylphenidate ; Methylphenidate - administration & dosage ; Methylphenidate - pharmacology ; Methylphenidate hydrochloride ; Neuropharmacology ; Neurosciences ; Original Investigation ; Pharmacology. Drug treatments ; Pharmacology/Toxicology ; Psychiatry ; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer ; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Psychopharmacology ; Smoke ; Smokers ; Smoking ; Smoking - epidemiology ; Tobacco smoking ; Tobacco, tobacco smoking ; Toxicology ; User statistics ; Young Adult</subject><ispartof>Psychopharmacologia, 2011-11, Vol.218 (2), p.381-390</ispartof><rights>Springer-Verlag 2011</rights><rights>2015 INIST-CNRS</rights><rights>COPYRIGHT 2011 Springer</rights><rights>Springer-Verlag 2011 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c597t-c0ba23b488a4cf3f50643735dfe2f2a3945098400c94fcbc1c1072c0920c17253</citedby><cites>FETCH-LOGICAL-c597t-c0ba23b488a4cf3f50643735dfe2f2a3945098400c94fcbc1c1072c0920c17253</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00213-011-2328-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00213-011-2328-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24693574$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21590284$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vansickel, Andrea R.</creatorcontrib><creatorcontrib>Stoops, William W.</creatorcontrib><creatorcontrib>Glaser, Paul E. A.</creatorcontrib><creatorcontrib>Poole, Megan M.</creatorcontrib><creatorcontrib>Rush, Craig R.</creatorcontrib><title>Methylphenidate increases cigarette smoking in participants with ADHD</title><title>Psychopharmacologia</title><addtitle>Psychopharmacology</addtitle><addtitle>Psychopharmacology (Berl)</addtitle><description>Rationale
Methylphenidate (Ritalin®) is commonly prescribed for behavioral problems associated with attention deficit/hyperactivity disorder (ADHD). The results of previous studies suggest that methylphenidate increases cigarette smoking in participants without psychiatric diagnoses. Whether methylphenidate increases cigarette smoking in participants diagnosed with ADHD is unknown.
Objective
In this within-subjects, repeated measures experiment, the acute effects of a range of doses of methylphenidate (10, 20, and 40 mg) and placebo were assessed in nine cigarette smokers who were not attempting to quit and met diagnostic criteria for ADHD but no other Axis I psychiatric disorders other than nicotine dependence.
Methods
Each dose of methylphenidate was tested once while placebo was tested twice. One hour after ingesting drug, participants were allowed to smoke ad libitum for 4 h. Measures of smoking included total cigarettes smoked, total puffs, and carbon monoxide levels. Snacks and decaffeinated drinks were available ad libitum; caloric intake during the 4-h smoking session was calculated.
Results
Methylphenidate increased the total number of cigarettes smoked, total number of puffs, and carbon monoxide levels. Methylphenidate decreased the number of food items consumed and caloric intake.
Conclusions
The results of this experiment suggest that acutely administered methylphenidate increases cigarette smoking in participants with ADHD, which is concordant with findings from previous studies that tested healthy young adults. These data indicate that clinicians may need to consider non-stimulant options or counsel their patients before starting methylphenidate when managing ADHD-diagnosed individuals who smoke.</description><subject>Acute effects</subject><subject>Addictive behaviors</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Attention Deficit Disorder with Hyperactivity - drug therapy</subject><subject>Attention deficit hyperactivity disorder</subject><subject>Beverages</subject><subject>Biological and medical sciences</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Carbon monoxide</subject><subject>Carbon Monoxide - analysis</subject><subject>Central Nervous System Stimulants - administration & dosage</subject><subject>Central Nervous System Stimulants - pharmacology</subject><subject>Cigarette smoking</subject><subject>Cigarettes</subject><subject>Data processing</subject><subject>Dose-Response Relationship, Drug</subject><subject>Double-Blind Method</subject><subject>Drug dependence</subject><subject>Drug therapy</subject><subject>Drugs</subject><subject>Eating - drug effects</subject><subject>Energy Intake - drug effects</subject><subject>Female</subject><subject>Food</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Hyperactivity</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mental disorders</subject><subject>Methylphenidate</subject><subject>Methylphenidate - administration & dosage</subject><subject>Methylphenidate - pharmacology</subject><subject>Methylphenidate hydrochloride</subject><subject>Neuropharmacology</subject><subject>Neurosciences</subject><subject>Original Investigation</subject><subject>Pharmacology. Drug treatments</subject><subject>Pharmacology/Toxicology</subject><subject>Psychiatry</subject><subject>Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer</subject><subject>Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychopharmacology</subject><subject>Smoke</subject><subject>Smokers</subject><subject>Smoking</subject><subject>Smoking - epidemiology</subject><subject>Tobacco smoking</subject><subject>Tobacco, tobacco smoking</subject><subject>Toxicology</subject><subject>User statistics</subject><subject>Young Adult</subject><issn>0033-3158</issn><issn>1432-2072</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kU1v1DAQhi0EokvhB3BBEQhxShl_beIL0qotFKmIC5wt76yddUmcYGdb7b_HUZaWotY-WJp55p0Zv4S8pnBCAaqPCYBRXgKlJeOsLvdPyIIKzkoGFXtKFgCcl5zK-oi8SOkK8hG1eE6OGJUKWC0W5PybHbf7dtja4DdmtIUPGK1JNhXoGxPtmGOp63_50ORcMZg4evSDCWMqbvy4LVZnF2cvyTNn2mRfHd5j8vPz-Y_Ti_Ly-5evp6vLEqWqxhJhbRhfi7o2Ah13EpaCV1xunGWOGa6EBFULAFTC4Rop0rwIgmKAtGKSH5NPs-6wW3d2gzaM0bR6iL4zca974_X9TPBb3fTXmtNaCcazwIeDQOx_72wadecT2rY1wfa7pBVbKshziEy-_Y-86ncx5O10rRTPwyyrDL2boca0Vvvg-twVJ0m94lLIqlJqmvrkASrfje089sE6n-P3CuhcgLFPKVp3uyEFPTmvZ-d1dl5Pzut9rnnz79fcVvy1OgPvD4BJaFoXTUCf7jixVFxWE8dmLuVUaGy8W_zx7n8AH7jEpA</recordid><startdate>20111101</startdate><enddate>20111101</enddate><creator>Vansickel, Andrea R.</creator><creator>Stoops, William W.</creator><creator>Glaser, Paul E. A.</creator><creator>Poole, Megan M.</creator><creator>Rush, Craig R.</creator><general>Springer-Verlag</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QR</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>5PM</scope></search><sort><creationdate>20111101</creationdate><title>Methylphenidate increases cigarette smoking in participants with ADHD</title><author>Vansickel, Andrea R. ; Stoops, William W. ; Glaser, Paul E. A. ; Poole, Megan M. ; Rush, Craig R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c597t-c0ba23b488a4cf3f50643735dfe2f2a3945098400c94fcbc1c1072c0920c17253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Acute effects</topic><topic>Addictive behaviors</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Attention Deficit Disorder with Hyperactivity - drug therapy</topic><topic>Attention deficit hyperactivity disorder</topic><topic>Beverages</topic><topic>Biological and medical sciences</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Carbon monoxide</topic><topic>Carbon Monoxide - analysis</topic><topic>Central Nervous System Stimulants - administration & dosage</topic><topic>Central Nervous System Stimulants - pharmacology</topic><topic>Cigarette smoking</topic><topic>Cigarettes</topic><topic>Data processing</topic><topic>Dose-Response Relationship, Drug</topic><topic>Double-Blind Method</topic><topic>Drug dependence</topic><topic>Drug therapy</topic><topic>Drugs</topic><topic>Eating - drug effects</topic><topic>Energy Intake - drug effects</topic><topic>Female</topic><topic>Food</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Hyperactivity</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mental disorders</topic><topic>Methylphenidate</topic><topic>Methylphenidate - administration & dosage</topic><topic>Methylphenidate - pharmacology</topic><topic>Methylphenidate hydrochloride</topic><topic>Neuropharmacology</topic><topic>Neurosciences</topic><topic>Original Investigation</topic><topic>Pharmacology. Drug treatments</topic><topic>Pharmacology/Toxicology</topic><topic>Psychiatry</topic><topic>Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer</topic><topic>Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Psychopharmacology</topic><topic>Smoke</topic><topic>Smokers</topic><topic>Smoking</topic><topic>Smoking - epidemiology</topic><topic>Tobacco smoking</topic><topic>Tobacco, tobacco smoking</topic><topic>Toxicology</topic><topic>User statistics</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vansickel, Andrea R.</creatorcontrib><creatorcontrib>Stoops, William W.</creatorcontrib><creatorcontrib>Glaser, Paul E. A.</creatorcontrib><creatorcontrib>Poole, Megan M.</creatorcontrib><creatorcontrib>Rush, Craig R.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Psychopharmacologia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vansickel, Andrea R.</au><au>Stoops, William W.</au><au>Glaser, Paul E. A.</au><au>Poole, Megan M.</au><au>Rush, Craig R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Methylphenidate increases cigarette smoking in participants with ADHD</atitle><jtitle>Psychopharmacologia</jtitle><stitle>Psychopharmacology</stitle><addtitle>Psychopharmacology (Berl)</addtitle><date>2011-11-01</date><risdate>2011</risdate><volume>218</volume><issue>2</issue><spage>381</spage><epage>390</epage><pages>381-390</pages><issn>0033-3158</issn><eissn>1432-2072</eissn><coden>PSYPAG</coden><abstract>Rationale
Methylphenidate (Ritalin®) is commonly prescribed for behavioral problems associated with attention deficit/hyperactivity disorder (ADHD). The results of previous studies suggest that methylphenidate increases cigarette smoking in participants without psychiatric diagnoses. Whether methylphenidate increases cigarette smoking in participants diagnosed with ADHD is unknown.
Objective
In this within-subjects, repeated measures experiment, the acute effects of a range of doses of methylphenidate (10, 20, and 40 mg) and placebo were assessed in nine cigarette smokers who were not attempting to quit and met diagnostic criteria for ADHD but no other Axis I psychiatric disorders other than nicotine dependence.
Methods
Each dose of methylphenidate was tested once while placebo was tested twice. One hour after ingesting drug, participants were allowed to smoke ad libitum for 4 h. Measures of smoking included total cigarettes smoked, total puffs, and carbon monoxide levels. Snacks and decaffeinated drinks were available ad libitum; caloric intake during the 4-h smoking session was calculated.
Results
Methylphenidate increased the total number of cigarettes smoked, total number of puffs, and carbon monoxide levels. Methylphenidate decreased the number of food items consumed and caloric intake.
Conclusions
The results of this experiment suggest that acutely administered methylphenidate increases cigarette smoking in participants with ADHD, which is concordant with findings from previous studies that tested healthy young adults. These data indicate that clinicians may need to consider non-stimulant options or counsel their patients before starting methylphenidate when managing ADHD-diagnosed individuals who smoke.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>21590284</pmid><doi>10.1007/s00213-011-2328-y</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Acute effects Addictive behaviors Adult Adult and adolescent clinical studies Attention Deficit Disorder with Hyperactivity - drug therapy Attention deficit hyperactivity disorder Beverages Biological and medical sciences Biomedical and Life Sciences Biomedicine Carbon monoxide Carbon Monoxide - analysis Central Nervous System Stimulants - administration & dosage Central Nervous System Stimulants - pharmacology Cigarette smoking Cigarettes Data processing Dose-Response Relationship, Drug Double-Blind Method Drug dependence Drug therapy Drugs Eating - drug effects Energy Intake - drug effects Female Food Health aspects Humans Hyperactivity Male Medical sciences Mental disorders Methylphenidate Methylphenidate - administration & dosage Methylphenidate - pharmacology Methylphenidate hydrochloride Neuropharmacology Neurosciences Original Investigation Pharmacology. Drug treatments Pharmacology/Toxicology Psychiatry Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Smoke Smokers Smoking Smoking - epidemiology Tobacco smoking Tobacco, tobacco smoking Toxicology User statistics Young Adult |
| title | Methylphenidate increases cigarette smoking in participants with ADHD |
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