Anti‐platelet therapy: ADP receptor antagonists

The P2Y12 receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis. Agents that act as antagonists at this receptor are thus likely to provide effective antithrombotic therapy, provided tha...

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Veröffentlicht in:	British journal of clinical pharmacology 2011-10, Vol.72 (4), p.647-657
Hauptverfasser:	Wijeyeratne, Yanushi Dullewe, Heptinstall, Stan
Format:	Artikel
Sprache:	eng
Schlagworte:	anti‐platelet Blood Platelets - drug effects cangrelor clopidogrel Haemostasis Themed Issue Humans P2Y12 platelet Platelet Aggregation - drug effects Platelet Aggregation Inhibitors - pharmacology prasugrel Purinergic P2Y Receptor Antagonists - pharmacology Thrombosis - prevention & control ticagrelor
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