New Nystatin-Related Antifungal Polyene Macrolides with Altered Polyol Region Generated via Biosynthetic Engineering of Streptomyces noursei
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| Veröffentlicht in: | Applied and Environmental Microbiology 2011-09, Vol.77 (18), p.6636-6643 |
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| creator | BRAUTASET, Trygve SLETTA, Havard DEGNES, Kristin F SEKUROVA, Olga N BAKKE, Ingrid VOLOKHAN, Olga ANDREASSEN, Trygve ELLINGSEN, Trond E ZOTCHEV, Sergey B |
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| doi_str_mv | 10.1128/AEM.05780-11 |
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</description><identifier>ISSN: 0099-2240</identifier><identifier>EISSN: 1098-5336</identifier><identifier>DOI: 10.1128/AEM.05780-11</identifier><identifier>PMID: 21764946</identifier><identifier>CODEN: AEMIDF</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>amphotericin B ; Animals ; Antibiotics ; Antifungal Agents - chemistry ; Antifungal Agents - metabolism ; Antifungal Agents - pharmacology ; Antifungal Agents - toxicity ; antifungal properties ; Biological and medical sciences ; Biosynthesis ; Biosynthetic Pathways - genetics ; Biotechnology ; Candida albicans - drug effects ; engineering ; Erythrocytes - drug effects ; Fundamental and applied biological sciences. Psychology ; Fungal infections ; Gram-positive bacteria ; Hemolysis ; Horses ; Macrolides - chemistry ; Macrolides - metabolism ; Macrolides - pharmacology ; Macrolides - toxicity ; Magnetic Resonance Spectroscopy ; Microbial Sensitivity Tests ; Microbiology ; Models, Molecular ; Molecular Structure ; nystatin ; Nystatin - analogs & derivatives ; Nystatin - chemistry ; Nystatin - metabolism ; Nystatin - pharmacology ; Nystatin - toxicity ; Polyenes - chemistry ; Polyenes - metabolism ; Polyenes - pharmacology ; Polyenes - toxicity ; Polymers - chemistry ; Polymers - metabolism ; Streptomyces - enzymology ; Streptomyces - genetics ; Streptomyces - metabolism ; Streptomyces noursei ; toxicity</subject><ispartof>Applied and Environmental Microbiology, 2011-09, Vol.77 (18), p.6636-6643</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright American Society for Microbiology Sep 2011</rights><rights>Copyright © 2011, American Society for Microbiology. All Rights Reserved. 2011 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c500t-d57ea0fd814cfab4764a5806e49a473f0ba9b25c392b035a2dbd5313bd85d8cd3</citedby><cites>FETCH-LOGICAL-c500t-d57ea0fd814cfab4764a5806e49a473f0ba9b25c392b035a2dbd5313bd85d8cd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187132/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3187132/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,3175,3176,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24524225$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21764946$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BRAUTASET, Trygve</creatorcontrib><creatorcontrib>SLETTA, Havard</creatorcontrib><creatorcontrib>DEGNES, Kristin F</creatorcontrib><creatorcontrib>SEKUROVA, Olga N</creatorcontrib><creatorcontrib>BAKKE, Ingrid</creatorcontrib><creatorcontrib>VOLOKHAN, Olga</creatorcontrib><creatorcontrib>ANDREASSEN, Trygve</creatorcontrib><creatorcontrib>ELLINGSEN, Trond E</creatorcontrib><creatorcontrib>ZOTCHEV, Sergey B</creatorcontrib><title>New Nystatin-Related Antifungal Polyene Macrolides with Altered Polyol Region Generated via Biosynthetic Engineering of Streptomyces noursei</title><title>Applied and Environmental Microbiology</title><addtitle>Appl Environ Microbiol</addtitle><description>Classifications
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</description><subject>amphotericin B</subject><subject>Animals</subject><subject>Antibiotics</subject><subject>Antifungal Agents - chemistry</subject><subject>Antifungal Agents - metabolism</subject><subject>Antifungal Agents - pharmacology</subject><subject>Antifungal Agents - toxicity</subject><subject>antifungal properties</subject><subject>Biological and medical sciences</subject><subject>Biosynthesis</subject><subject>Biosynthetic Pathways - genetics</subject><subject>Biotechnology</subject><subject>Candida albicans - drug effects</subject><subject>engineering</subject><subject>Erythrocytes - drug effects</subject><subject>Fundamental and applied biological sciences. 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Psychology</topic><topic>Fungal infections</topic><topic>Gram-positive bacteria</topic><topic>Hemolysis</topic><topic>Horses</topic><topic>Macrolides - chemistry</topic><topic>Macrolides - metabolism</topic><topic>Macrolides - pharmacology</topic><topic>Macrolides - toxicity</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Microbial Sensitivity Tests</topic><topic>Microbiology</topic><topic>Models, Molecular</topic><topic>Molecular Structure</topic><topic>nystatin</topic><topic>Nystatin - analogs & derivatives</topic><topic>Nystatin - chemistry</topic><topic>Nystatin - metabolism</topic><topic>Nystatin - pharmacology</topic><topic>Nystatin - toxicity</topic><topic>Polyenes - chemistry</topic><topic>Polyenes - metabolism</topic><topic>Polyenes - pharmacology</topic><topic>Polyenes - toxicity</topic><topic>Polymers - chemistry</topic><topic>Polymers - metabolism</topic><topic>Streptomyces - enzymology</topic><topic>Streptomyces - genetics</topic><topic>Streptomyces - metabolism</topic><topic>Streptomyces noursei</topic><topic>toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BRAUTASET, Trygve</creatorcontrib><creatorcontrib>SLETTA, Havard</creatorcontrib><creatorcontrib>DEGNES, Kristin F</creatorcontrib><creatorcontrib>SEKUROVA, Olga N</creatorcontrib><creatorcontrib>BAKKE, Ingrid</creatorcontrib><creatorcontrib>VOLOKHAN, Olga</creatorcontrib><creatorcontrib>ANDREASSEN, Trygve</creatorcontrib><creatorcontrib>ELLINGSEN, Trond E</creatorcontrib><creatorcontrib>ZOTCHEV, Sergey B</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Environment Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>Environment Abstracts</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Applied and Environmental Microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BRAUTASET, Trygve</au><au>SLETTA, Havard</au><au>DEGNES, Kristin F</au><au>SEKUROVA, Olga N</au><au>BAKKE, Ingrid</au><au>VOLOKHAN, Olga</au><au>ANDREASSEN, Trygve</au><au>ELLINGSEN, Trond E</au><au>ZOTCHEV, Sergey B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>New Nystatin-Related Antifungal Polyene Macrolides with Altered Polyol Region Generated via Biosynthetic Engineering of Streptomyces noursei</atitle><jtitle>Applied and Environmental Microbiology</jtitle><addtitle>Appl Environ Microbiol</addtitle><date>2011-09-01</date><risdate>2011</risdate><volume>77</volume><issue>18</issue><spage>6636</spage><epage>6643</epage><pages>6636-6643</pages><issn>0099-2240</issn><eissn>1098-5336</eissn><coden>AEMIDF</coden><abstract>Classifications
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>21764946</pmid><doi>10.1128/AEM.05780-11</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0099-2240 |
| ispartof | Applied and Environmental Microbiology, 2011-09, Vol.77 (18), p.6636-6643 |
| issn | 0099-2240 1098-5336 |
| language | eng |
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| source | American Society for Microbiology; MEDLINE; PubMed Central; Alma/SFX Local Collection |
| subjects | amphotericin B Animals Antibiotics Antifungal Agents - chemistry Antifungal Agents - metabolism Antifungal Agents - pharmacology Antifungal Agents - toxicity antifungal properties Biological and medical sciences Biosynthesis Biosynthetic Pathways - genetics Biotechnology Candida albicans - drug effects engineering Erythrocytes - drug effects Fundamental and applied biological sciences. Psychology Fungal infections Gram-positive bacteria Hemolysis Horses Macrolides - chemistry Macrolides - metabolism Macrolides - pharmacology Macrolides - toxicity Magnetic Resonance Spectroscopy Microbial Sensitivity Tests Microbiology Models, Molecular Molecular Structure nystatin Nystatin - analogs & derivatives Nystatin - chemistry Nystatin - metabolism Nystatin - pharmacology Nystatin - toxicity Polyenes - chemistry Polyenes - metabolism Polyenes - pharmacology Polyenes - toxicity Polymers - chemistry Polymers - metabolism Streptomyces - enzymology Streptomyces - genetics Streptomyces - metabolism Streptomyces noursei toxicity |
| title | New Nystatin-Related Antifungal Polyene Macrolides with Altered Polyol Region Generated via Biosynthetic Engineering of Streptomyces noursei |
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