Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) is characterized by a series of pathological changes that range from simple fatty liver to nonalcoholic steatohepatitis (NASH). The objective of this study is to describe changes in global gene expression associated with the progression of human NAFLD. This s...

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Veröffentlicht in:	Drug metabolism and disposition 2011-10, Vol.39 (10), p.1954-1960
Hauptverfasser:	Lake, April D., Novak, Petr, Fisher, Craig D., Jackson, Jonathan P., Hardwick, Rhiannon N., Billheimer, D. Dean, Klimecki, Walter T., Cherrington, Nathan J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Biological and medical sciences Biological Transport Disease Progression Down-Regulation Fatty Liver - genetics Fatty Liver - metabolism Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Genome-Wide Association Study - methods Humans Liver - metabolism Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Microarray Analysis - methods Non-alcoholic Fatty Liver Disease Other diseases. Semiology Pharmaceutical Preparations - metabolism Pharmacology. Drug treatments RNA, Messenger - genetics Tissue Distribution
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