Neuroprotection by Spice-Derived Nutraceuticals: You Are What You Eat
Numerous lines of evidence indicate that chronic inflammation plays a major role in the development of various neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, brain tumor, and meningitis. Why these diseases are more common among people from some co...
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| Veröffentlicht in: | Molecular neurobiology 2011-10, Vol.44 (2), p.142-159 |
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| creator | Kannappan, Ramaswamy Gupta, Subash Chandra Kim, Ji Hye Reuter, Simone Aggarwal, Bharat Bhushan |
| description | Numerous lines of evidence indicate that chronic inflammation plays a major role in the development of various neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, brain tumor, and meningitis. Why these diseases are more common among people from some countries than others is not fully understood, but lifestyle factors have been linked to the development of neurodegenerative diseases. For example, the incidence of certain neurodegenerative diseases among people living in the Asian subcontinent, where people regularly consume spices, is much lower than in countries of the western world. Extensive research over the last 10 years has indicated that nutraceuticals derived from such spices as turmeric, red pepper, black pepper, licorice, clove, ginger, garlic, coriander, and cinnamon target inflammatory pathways, thereby may prevent neurodegenerative diseases. How these nutraceuticals modulate various pathways and how they exert neuroprotection are the focus of this review. |
| doi_str_mv | 10.1007/s12035-011-8168-2 |
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Why these diseases are more common among people from some countries than others is not fully understood, but lifestyle factors have been linked to the development of neurodegenerative diseases. For example, the incidence of certain neurodegenerative diseases among people living in the Asian subcontinent, where people regularly consume spices, is much lower than in countries of the western world. Extensive research over the last 10 years has indicated that nutraceuticals derived from such spices as turmeric, red pepper, black pepper, licorice, clove, ginger, garlic, coriander, and cinnamon target inflammatory pathways, thereby may prevent neurodegenerative diseases. 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Why these diseases are more common among people from some countries than others is not fully understood, but lifestyle factors have been linked to the development of neurodegenerative diseases. For example, the incidence of certain neurodegenerative diseases among people living in the Asian subcontinent, where people regularly consume spices, is much lower than in countries of the western world. Extensive research over the last 10 years has indicated that nutraceuticals derived from such spices as turmeric, red pepper, black pepper, licorice, clove, ginger, garlic, coriander, and cinnamon target inflammatory pathways, thereby may prevent neurodegenerative diseases. 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| subjects | Allium sativum Animals Biomedical and Life Sciences Biomedicine Brain Neoplasms - drug therapy Cell Biology Clinical Trials as Topic Curcuma longa Diet Dietary Supplements Food Glycyrrhiza glabra Humans Inflammation - complications Inflammation - prevention & control Molecular Structure Neurobiology Neurodegenerative Diseases - etiology Neurodegenerative Diseases - prevention & control Neurological disorders Neurology Neuroprotective Agents - therapeutic use Neurosciences Piper nigrum Plant Extracts - chemistry Plant Extracts - therapeutic use Spices |
| title | Neuroprotection by Spice-Derived Nutraceuticals: You Are What You Eat |
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