CSF1 Expression in Nongynecological Leiomyosarcoma Is Associated with Increased Tumor Angiogenesis

Leiomyosarcoma (LMS) is a malignant tumor of smooth muscle cells for which few effective therapies exist. A subset of LMS cases express macrophage colony-stimulating factor (CSF1) and the resultant tumor-associated macrophage (TAM) infiltration predicts poor clinical outcome. Further, TAMs have been...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of pathology 2011-10, Vol.179 (4), p.2100-2107
Hauptverfasser:	Espinosa, Iñigo, Edris, Badreddin, Lee, Cheng-Han, Cheng, Hong Wei, Gilks, C. Blake, Wang, Yuzhuo, Montgomery, Kelli D, Varma, Sushama, Li, Rui, Marinelli, Robert J, West, Robert B, Nielsen, Torsten, Beck, Andrew H, van de Rijn, Matt
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Animals Antigens, CD34 - metabolism Biological and medical sciences Biomarkers, Tumor - metabolism Dermatology Female Gene Expression Regulation, Neoplastic Humans Investigative techniques, diagnostic techniques (general aspects) Leiomyosarcoma - blood supply Leiomyosarcoma - genetics Leiomyosarcoma - pathology Macrophage Colony-Stimulating Factor - genetics Macrophage Colony-Stimulating Factor - metabolism Macrophages - metabolism Macrophages - pathology Male Medical sciences Mice Microvessels - metabolism Microvessels - pathology Middle Aged Neovascularization, Pathologic - metabolism Neovascularization, Pathologic - pathology Pathology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Prognosis Regular Tumors of the skin and soft tissue. Premalignant lesions Vascular Endothelial Growth Factor A - metabolism Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!