Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides

We have studied the translation of rabbit globin mRNA in cell free systems (reticulocyte lysate and wheat germ extract) and in microinjected Xenopus oocytes in the presence of anti-sense oligodeoxynucleotides. Results obtained with the unmodified all-oxygen compounds were compared with those obtaine...

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Veröffentlicht in:	Nucleic acids research 1989-06, Vol.17 (11), p.4255-4273
Hauptverfasser:	CAZENAVE, C, STEIN, C. A, LOREAU, N, THUONG, N. T, NECKERS, L. M, SUBASINGHE, C, HELENE, C, COHEN, J. S, TOULME, J.-J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Binding, Competitive Biological and medical sciences Cell-Free System Fundamental and applied biological sciences. Psychology Globins - genetics Globins - metabolism Molecular and cellular biology Molecular genetics Molecular Sequence Data Nucleic Acid Hybridization Oligonucleotide Probes - chemical synthesis Oligonucleotide Probes - pharmacology Oocytes - metabolism Protein Biosynthesis Rabbits Reticulocytes - metabolism Ribonucleases - metabolism RNA RNA, Antisense RNA, Messenger - genetics RNA, Messenger - metabolism Thermodynamics Translation. Translation factors. Protein processing Triticum - genetics Triticum aestivum Xenopus Xenopus - genetics
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