Decreased expression of ATP6V1H in type 2 diabetes: A pilot report on the diabetes risk study in Mexican Americans

► This prospective study investigated gene expression in progress of diabetes in human. ► ATP6V1H in peripheral blood decreased with progression from pre-diabetes to diabetes. ► This observation casts new light on the mechanisms involved in diabetes and its complications. Previous studies in mice an...

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Veröffentlicht in:	Biochemical and biophysical research communications 2011-09, Vol.412 (4), p.728-731
Hauptverfasser:	Molina, Melanie F., Qu, Hui-Qi, Rentfro, Anne R., Nair, Saraswathy, Lu, Yang, Hanis, Craig L., McCormick, Joseph B., Fisher-Hoch, Susan P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged ATP6V1H blood Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Diabetic complications Down-Regulation gene expression Humans Longitudinal study Male messenger RNA Mexican Americans mice Middle Aged noninsulin-dependent diabetes mellitus Pilot Projects Risk RNA, Messenger - biosynthesis Tissue Distribution Transcriptome Type 2 diabetes United States - epidemiology United States - ethnology Vacuolar ATPase Vacuolar Proton-Translocating ATPases - blood Vacuolar Proton-Translocating ATPases - genetics
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