Quantification of inbreeding due to distant ancestors and its detection using dense single nucleotide polymorphism data

Inbreeding depression, which refers to reduced fitness among offspring of related parents, has traditionally been studied using pedigrees. In practice, pedigree information is difficult to obtain, potentially unreliable, and rarely assessed for inbreeding arising from common ancestors who lived more...

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Veröffentlicht in:Genetics (Austin) 2011-09, Vol.189 (1), p.237-249
Hauptverfasser: Keller, Matthew C, Visscher, Peter M, Goddard, Michael E
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Sprache:eng
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