Myc activates telomerase

Telomere maintenance has been proposed as an essential prerequisite to human tumor development. The telomerase enzyme is itself a marker for tumor cells, but the genetic alterations that activate the enzyme during neoplastic transformation have remained a mystery. Here, we show that Myc induces telo...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Genes & development 1998-06, Vol.12 (12), p.1769-1774
Hauptverfasser:	Wang, J, Xie, L Y, Allan, S, Beach, D, Hannon, G J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Division - physiology Cell Line DNA-Binding Proteins Enzyme Activation - genetics Gene Expression - genetics Humans Proteins - genetics Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - physiology Recombinant Proteins - genetics Research Communication RNA RNA, Messenger - metabolism Telomerase - genetics Tumor Cells, Cultured - enzymology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!