Negative regulation of male development in Caenorhabditis elegans by a protein-protein interaction between TRA-2A and FEM-3

The tra-2 gene of the nematode Caenorhabditis elegans encodes a predicted membrane protein, TRA-2A, that promotes XX hermaphrodite development. Genetic analysis suggests that tra-2 is a negative regulator of three genes that are required for male development: fem-1, fem-2, and fem-3. We report that...

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Veröffentlicht in:	Genes & development 1999-06, Vol.13 (11), p.1453-1463
Hauptverfasser:	Mehra, A, Gaudet, J, Heck, L, Kuwabara, P E, Spence, A M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites Caenorhabditis elegans Caenorhabditis elegans - genetics Caenorhabditis elegans - physiology Caenorhabditis elegans Proteins Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cloning, Molecular Female Heat-Shock Response Helminth Proteins - genetics Helminth Proteins - metabolism Male Membrane Proteins - genetics Membrane Proteins - metabolism Phosphoprotein Phosphatases Research Paper Saccharomyces cerevisiae Sex Differentiation - genetics Transgenes
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