Developmental profiling of spiral ganglion neurons reveals insights into auditory circuit assembly

The sense of hearing depends on the faithful transmission of sound information from the ear to the brain by spiral ganglion (SG) neurons. However, how SG neurons develop the connections and properties that underlie auditory processing is largely unknown. We catalogued gene expression in mouse SG neu...

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Veröffentlicht in:	The Journal of neuroscience 2011-07, Vol.31 (30), p.10903-10918
Hauptverfasser:	Lu, Cindy C, Appler, Jessica M, Houseman, E Andres, Goodrich, Lisa V
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Animals Animals, Newborn Axons - physiology Bone Morphogenetic Protein Receptors - genetics Bone Morphogenetic Protein Receptors - metabolism Cluster Analysis Embryo, Mammalian GATA3 Transcription Factor - genetics GATA3 Transcription Factor - metabolism Gene Expression Profiling Gene Expression Regulation, Developmental - physiology Gene Regulatory Networks - physiology Green Fluorescent Proteins - genetics Homeodomain Proteins - genetics In Vitro Techniques MafB Transcription Factor - genetics Mice Mice, Transgenic Nerve Net - physiology Neurons - cytology Neurons - physiology Oligonucleotide Array Sequence Analysis PubMed - statistics & numerical data Receptor, EphA5 - genetics Receptor, EphA5 - metabolism Receptors, Atrial Natriuretic Factor - genetics Reproducibility of Results Spiral Ganglion - cytology Spiral Ganglion - embryology Transcription Factors - genetics Transcription Factors - metabolism Transforming Growth Factor beta - genetics Transforming Growth Factor beta - metabolism
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