Peripheral and Central Fat Changes in Subjects Randomized to Abacavir-Lamivudine or Tenofovir-Emtricitabine With Atazanavir-Ritonavir or Efavirenz: ACTG Study A5224s

Background. We compare the effect of 4 different antiretroviral regimens on limb and visceral fat. Methods. A5224s was a substudy of A5202, a trial of human immunodeficiency virus type 1 (HIV-1)—infected, treatment-naive subjects randomized to blinded abacavir-lamivudine (ABC-3TC) or tenofovir DF-em...

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Veröffentlicht in:	Clinical infectious diseases 2011-07, Vol.53 (2), p.185-196
Hauptverfasser:	McComsey, Grace A., Kitch, Douglas, Sax, Paul E., Tebas, Pablo, Tierney, Camlin, Jahed, Nasreen C., Myers, Laurie, Melbourne, Kathleen, Ha, Belinda, Daar, Eric S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissues Adult Anti-HIV Agents - administration & dosage Anti-HIV Agents - adverse effects Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral drugs Antiretroviral Therapy, Highly Active - adverse effects Antiretroviral Therapy, Highly Active - methods Antiviral agents Biological and medical sciences Body fat Body Fat Distribution Body mass index Clinical trials Drug therapy Fats Female HIV HIV 1 HIV Infections - drug therapy HIV Infections - virology HIV-1 - isolation & purification HIV-Associated Lipodystrophy Syndrome - chemically induced HIV/AIDS Human immunodeficiency virus Human immunodeficiency virus 1 Humans Infectious diseases Male Medical sciences Middle Aged Pharmacology. Drug treatments Random allocation Registered nurses RNA Visceral fat
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