Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box protein complexes that regulate cell division and methionine biosynthesis in yeast

In budding yeast, ubiquitination of the cyclin-dependent kinase (Cdk) inhibitor Sic1 is catalyzed by the E2 ubiquitin conjugating enzyme Cdc34 in conjunction with an E3 ubiquitin ligase complex composed of Skp1, Cdc53 and the F-box protein, Cdc4 (the SCF super(Cdc4) complex). Skp1 binds a motif call...

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Veröffentlicht in:	Genes & development 1998-03, Vol.12 (5), p.692-705
Hauptverfasser:	Patton, E. E., Willems, A. R., Sa, D., Kuras, L., Thomas, D., Craig, K. L., Tyers, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Research Paper
Online-Zugang:	Volltext
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