Within-session analysis of amphetamine-elicited rotation behavior reveals differences between young adult and middle-aged F344/BN rats with partial unilateral striatal dopamine depletion

Preclinical modeling of Parkinson's disease using 6-hydroxydopamine (6-OHDA) has been valuable in developing and testing therapeutic strategies. Recent efforts have focused on modeling early stages of disease by infusing 6-OHDA into the striatum. The partial DA depletion that follows intrastria...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2010-10, Vol.96 (4), p.423-428
Hauptverfasser:	Bethel-Brown, Crystal S., Zhang, Hongyu, Fowler, Stephen C., Chertoff, Mark E., Watson, G. Stennis, Stanford, John A.
Format:	Artikel
Sprache:	eng
Schlagworte:	3,4-Dihydroxyphenylacetic Acid - metabolism Adult and adolescent clinical studies Age Factors Amphetamine Amphetamines - pharmacology Animal models Animals Basal ganglia Behavior, Animal - drug effects Behavioral assay Biological and medical sciences Corpus Striatum - drug effects Corpus Striatum - metabolism Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dopamine - metabolism Medical sciences Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Neuropharmacology Organic mental disorders. Neuropsychology Oxidopamine - pharmacology Parkinson's disease Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychopharmacology Rats Rats, Inbred F344 Rotation Striatum
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!