Showcasing modern molecular dynamics simulations of membrane proteins through G protein-coupled receptors

► GPCRs as an example to showcase cutting-edge molecular dynamics simulations. ► Brief introduction to all-atom, coarse-grained, and biased MD simulation strategies. ► Focus on studies addressing GPCR ligand recognition, activation, and oligomerization. Despite many years of dedicated efforts, high-...

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Veröffentlicht in:	Current opinion in structural biology 2011-08, Vol.21 (4), p.552-558
Hauptverfasser:	Johnston, Jennifer M, Filizola, Marta
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ligands Molecular Dynamics Simulation Protein Multimerization Protein Structure, Quaternary Receptors, G-Protein-Coupled - chemistry Receptors, G-Protein-Coupled - metabolism
Online-Zugang:	Volltext
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