Development of a “Modular” Scheme to Describe the Kinetics of Transcript Elongation by RNA Polymerase

Transcript elongation by RNA polymerase involves the sequential appearance of several alternative and off-pathway states of the transcript elongation complex (TEC), and this complicates modeling of the kinetics of the transcription elongation process. Based on solutions of the chemical master equati...

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Veröffentlicht in:	Biophysical journal 2011-09, Vol.101 (5), p.1155-1165
Hauptverfasser:	Greive, Sandra J., Goodarzi, Jim P., Weitzel, Steven E., von Hippel, Peter H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cofactors Deoxyribonucleic acid DNA DNA-directed RNA polymerase DNA-Directed RNA Polymerases - metabolism electrophoresis equations Kinetics Models, Genetic Nucleic Acid RNA polymerase RNA, Messenger - genetics RNA, Messenger - metabolism Simulation surface plasmon resonance transcription (genetics) Transcription, Genetic
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