Mania associated with complicated hereditary spastic paraparesis
Hereditary spastic paraparesis (HSP) is an inherited group of neurological disorders with progressive lower limb spasticity. HSP can be clinically grouped into pure and complicated forms. Pure HSP is one without any associated neurological/psychiatric comorbidity. Depression is the most common psych...
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| Veröffentlicht in: | Journal of neurosciences in rural practice 2011-07, Vol.2 (2), p.190-192 |
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| creator | Nayak, Raghavendra B Bhogale, Govind S Patil, Nanasaheb M Pandurangi, Aditya A |
| description | Hereditary spastic paraparesis (HSP) is an inherited group of neurological disorders with progressive lower limb spasticity. HSP can be clinically grouped into pure and complicated forms. Pure HSP is one without any associated neurological/psychiatric comorbidity. Depression is the most common psychiatric comorbidity. Presence of mania or bipolar affective illness with HSP is a rare phenomenon. We report a case of a 17-year-old boy who presented with classical features of HSP with complaints of excessive happiness, irritability, increased self-esteem and decreased sleep since 1 month. The patient also had complex partial seizure ever since he had features of HSP. The patient's father and younger sister suffer from pure HSP. The patient was diagnosed to have first episode mania with complicated HSP. The details of treatment and possible neurobiology are discussed in this case report. |
| doi_str_mv | 10.4103/0976-3147.83592 |
| format | Article |
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HSP can be clinically grouped into pure and complicated forms. Pure HSP is one without any associated neurological/psychiatric comorbidity. Depression is the most common psychiatric comorbidity. Presence of mania or bipolar affective illness with HSP is a rare phenomenon. We report a case of a 17-year-old boy who presented with classical features of HSP with complaints of excessive happiness, irritability, increased self-esteem and decreased sleep since 1 month. The patient also had complex partial seizure ever since he had features of HSP. The patient's father and younger sister suffer from pure HSP. The patient was diagnosed to have first episode mania with complicated HSP. 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HSP can be clinically grouped into pure and complicated forms. Pure HSP is one without any associated neurological/psychiatric comorbidity. Depression is the most common psychiatric comorbidity. Presence of mania or bipolar affective illness with HSP is a rare phenomenon. We report a case of a 17-year-old boy who presented with classical features of HSP with complaints of excessive happiness, irritability, increased self-esteem and decreased sleep since 1 month. The patient also had complex partial seizure ever since he had features of HSP. The patient's father and younger sister suffer from pure HSP. The patient was diagnosed to have first episode mania with complicated HSP. The details of treatment and possible neurobiology are discussed in this case report.</description><subject>Bipolar disorder</subject><subject>Case Report</subject><subject>Case studies</subject><subject>Complications and side effects</subject><subject>Genetic aspects</subject><subject>Heat shock proteins</subject><subject>Mania</subject><subject>Nervous system diseases</subject><subject>Neurological disorders</subject><subject>Physiological aspects</subject><subject>Risk factors</subject><issn>0976-3147</issn><issn>0976-3155</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptUUtLAzEYDKJY0Z69yaLntnntJrmIIr6g4kXPIc2jTelu1mSr-O9NHxYLJoSE75sZJt8AcI7gkCJIRlCwakAQZUNOSoEPwMm2UpaHuzdlPdBPaQ7zIgQhyI5BDyOeu1ycgJsX1XhVqJSC9qqzpvjy3azQoW4XXq8LMxut8Z2K30VqVeq8LloVVT42-XQGjpxaJNvf3qfg_eH-7e5pMH59fL67HQ80hbwbmJJCRAWB3BprcEVLZgSDjjnEMKauVJArPeGTyjLKtLKVc8g4wxiecAEFOQXXG912Oamt0bbpolrINvo6O5NBebnfafxMTsOnzOMQpMJZ4HIrEMPH0qZOzsMyNtmz5Hl-uETlCnS1AU3VwkrfuJC1dO2TlrfZNCGC4Sqjhv-g8ja29jo01vlc3yOMNgQdQ0rRup1vBOUqS7lKS67SkussM-Pi73d3-N_kyA8tLZjG</recordid><startdate>20110701</startdate><enddate>20110701</enddate><creator>Nayak, Raghavendra B</creator><creator>Bhogale, Govind S</creator><creator>Patil, Nanasaheb M</creator><creator>Pandurangi, Aditya A</creator><general>Medknow Publications and Media Pvt. 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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; PubMed Central Open Access; Thieme Connect Journals Open Access |
| subjects | Bipolar disorder Case Report Case studies Complications and side effects Genetic aspects Heat shock proteins Mania Nervous system diseases Neurological disorders Physiological aspects Risk factors |
| title | Mania associated with complicated hereditary spastic paraparesis |
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