Expression of Endoplasmic Reticulum Stress Proteins Is a Candidate Marker of Brain Metastasis in both ErbB-2+ and ErbB-2− Primary Breast Tumors

The increasing incidence of breast cancer brain metastasis in patients with otherwise well-controlled systemic cancer is a key challenge in cancer research. It is necessary to understand the properties of brain-tropic tumor cells to identify patients at risk for brain metastasis. Here we attempt to...

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Veröffentlicht in:	The American journal of pathology 2011-08, Vol.179 (2), p.564-579
Hauptverfasser:	Sanz-Pamplona, Rebeca, Aragüés, Ramón, Driouch, Keltouma, Martín, Berta, Oliva, Baldo, Gil, Miguel, Boluda, Susana, Fernández, Pedro L, Martínez, Antonio, Moreno, Víctor, Acebes, Juan J, Lidereau, Rosette, Reyal, Fabien, Van de Vijver, Marc J, Sierra, Angels
Format:	Artikel
Sprache:	eng
Schlagworte:	Area Under Curve Biological and medical sciences Biomarkers, Tumor - metabolism Bone Neoplasms - secondary Brain Neoplasms - metabolism Brain Neoplasms - secondary Breast Neoplasms - metabolism Cervell Càncer Disease Progression Endoplasmic Reticulum - metabolism Female Gene Expression Regulation, Neoplastic Gynecology. Andrology. Obstetrics Humans Inhibins - biosynthesis Investigative techniques, diagnostic techniques (general aspects) Liver Neoplasms - secondary Lung Neoplasms - secondary Mammary gland diseases Medical sciences Membrane Glycoproteins - biosynthesis Neoplasm Metastasis Neurology Ossos Pathology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Receptor, ErbB-2 - biosynthesis Receptors, Tumor Necrosis Factor - biosynthesis Regulació genètica Regular Tumors Tumors of the nervous system. Phacomatoses TWEAK Receptor
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