Expression of the inflammatory chemokines CCL2, CCL5 and CXCL2 and the receptors CCR1–3 and CXCR2 in T lymphocytes from mammary tumor-bearing mice

► T lymphocytes from mammary tumor-bearing mice express CCL2, CCL5 and CXCL2. ► Chemokine receptors CCR-1, -2, -3 and CXCR2 are upregulated in T lymphocytes of tumor-bearing mice. ► Both splenic T cells and tumor-infiltrating T lymphocytes express CCL2 and CCL5 as well as CCR1. ► CCL2 induces the ex...

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Veröffentlicht in:	Cellular immunology 2011, Vol.270 (2), p.172-182
Hauptverfasser:	Owen, Jennifer L., Criscitiello, Michael F., Libreros, Stephania, Garcia-Areas, Ramon, Guthrie, Kathleen, Torroella-Kouri, Marta, Iragavarapu-Charyulu, Vijaya
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - immunology Angiogenesis Animals Cell Line, Tumor Chemokine CCL2 - genetics Chemokine CCL2 - metabolism Chemokine CCL2 - pharmacology Chemokine CCL5 - genetics Chemokine CCL5 - metabolism Chemokine CXCL2 - genetics Chemokine CXCL2 - metabolism Chemokine receptors Chemokines Chemokines - genetics Chemokines - metabolism Female Gene Expression Inflammation Mediators - metabolism Lymphocytes, Tumor-Infiltrating - immunology Mammary Neoplasms, Experimental - genetics Mammary Neoplasms, Experimental - immunology Mammary tumor Mice Mice, Inbred BALB C Receptors, CCR1 - genetics Receptors, CCR1 - metabolism Receptors, CCR2 - genetics Receptors, CCR2 - metabolism Receptors, CCR3 - genetics Receptors, CCR3 - metabolism Receptors, Chemokine - genetics Receptors, Chemokine - metabolism Receptors, Interleukin-8B - genetics Receptors, Interleukin-8B - metabolism Recombinant Proteins - pharmacology RNA, Messenger - genetics RNA, Neoplasm - genetics T lymphocytes T-Lymphocyte Subsets - immunology T-Lymphocytes - immunology
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