Acrocyanosis: The Flying Dutchman

Acrocyanosis is symmetric, painless, discoloration of different shades of blue in the distal parts of the body that is marked by symmetry, relative persistence of the skin color changes with aggravation by cold exposure, and frequent association with local hyperhidrosis of hands and feet. Described...

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Veröffentlicht in:Vascular Medicine 2011-08, Vol.16 (4), p.288-301
Hauptverfasser: Kurklinsky, Andrew K, Miller, Virginia M, Rooke, Thom W
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creator Kurklinsky, Andrew K
Miller, Virginia M
Rooke, Thom W
description Acrocyanosis is symmetric, painless, discoloration of different shades of blue in the distal parts of the body that is marked by symmetry, relative persistence of the skin color changes with aggravation by cold exposure, and frequent association with local hyperhidrosis of hands and feet. Described over a century ago and despite seeming familiarity, it remains a poorly understood condition that shares much in clinical presentation with other conditions characterized by skin color changes in the distal parts of the body. The diagnosis remains mostly clinical, and pathological mechanisms vary suggesting that acrocyanosis may not be a single entity. We performed an extensive literature review to summarize existing knowledge about the demographics, pathology, diagnosis, and treatment of this condition.
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Described over a century ago and despite seeming familiarity, it remains a poorly understood condition that shares much in clinical presentation with other conditions characterized by skin color changes in the distal parts of the body. The diagnosis remains mostly clinical, and pathological mechanisms vary suggesting that acrocyanosis may not be a single entity. We performed an extensive literature review to summarize existing knowledge about the demographics, pathology, diagnosis, and treatment of this condition.</description><identifier>ISSN: 1358-863X</identifier><identifier>EISSN: 1477-0377</identifier><identifier>DOI: 10.1177/1358863X11398519</identifier><identifier>PMID: 21427140</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. 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subjects Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Cyanosis - diagnosis
Cyanosis - epidemiology
Cyanosis - physiopathology
Cyanosis - therapy
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Humans
Lower Extremity - blood supply
Medical sciences
Predictive Value of Tests
Regional Blood Flow
Risk Factors
Treatment Outcome
Upper Extremity - blood supply
title Acrocyanosis: The Flying Dutchman
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