ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function

A disintegrin and metalloproteinase (ADAM) represents a protein family possessing both metalloproteinase and disintegrin domains. ADAMTS-1, an ADAM family member cloned from cachexigenic colon adenocarcinoma, is unusual in that it contains thrombospondin type I motifs and anchors to the extracellula...

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Veröffentlicht in:	The Journal of clinical investigation 2000-05, Vol.105 (10), p.1345-1352
Hauptverfasser:	Shindo, T, Kurihara, H, Kuno, K, Yokoyama, H, Wada, T, Kurihara, Y, Imai, T, Wang, Y, Ogata, M, Nishimatsu, H, Moriyama, N, Oh-hashi, Y, Morita, H, Ishikawa, T, Nagai, R, Yazaki, Y, Matsushima, K
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAM Proteins ADAMTS1 Protein Adrenal Glands - abnormalities Animals Disintegrins - chemistry Disintegrins - genetics Disintegrins - physiology Female Fertility - genetics Fertility - physiology Growth - genetics Growth - physiology Humans Infertility, Female - etiology Kidney - abnormalities Male Metalloendopeptidases - chemistry Metalloendopeptidases - genetics Metalloendopeptidases - physiology Mice Mice, Inbred C57BL Mice, Knockout Ovary - abnormalities Phenotype Pregnancy Uterus - abnormalities
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