Visinin-like protein-1: Diagnostic and prognostic biomarker in Alzheimer disease

Objective: There is a growing need to identify cerebrospinal fluid (CSF) markers that can detect Alzheimer's disease (AD) pathology in cognitively normal individuals because it is in this population that disease‐modifying therapies may have the greatest chance of success. While AD pathology is...

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Veröffentlicht in:	Annals of neurology 2011-08, Vol.70 (2), p.274-285
Hauptverfasser:	Tarawneh, Rawan, D'Angelo, Gina, Macy, Elizabeth, Xiong, Chengjie, Carter, Deborah, Cairns, Nigel J., Fagan, Anne M., Head, Denise, Mintun, Mark A., Ladenson, Jack H., Lee, Jin-Moo, Morris, John C., Holtzman, David M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Alzheimer Disease - blood Alzheimer Disease - cerebrospinal fluid Alzheimer Disease - diagnosis Alzheimer Disease - physiopathology Amyloid beta-Peptides - blood Amyloid beta-Peptides - cerebrospinal fluid Biological and medical sciences Biomarkers - blood Biomarkers - cerebrospinal fluid Brain Cognitive ability Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Humans Magnetic Resonance Imaging Male Medical research Medical sciences Middle Aged Neurocalcin - blood Neurocalcin - cerebrospinal fluid Neurology Prognosis ROC Curve tau Proteins - blood tau Proteins - cerebrospinal fluid
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