Comparison of the effect of vanadium and deferoxamine on acetaminophen toxicity in rats

Aim: Acetaminophen (APAP) can change to toxic metabolites at high dose; if these metabolites are in high amounts, the body will be unable to neutralize them, and several tissues including liver will be damaged. In the present study, the effect of vanadium was compared with deferoxamine on hepatotoxi...

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Veröffentlicht in:	Indian journal of pharmacology 2011-07, Vol.43 (4), p.429-432
Hauptverfasser:	Najafzadeh, H, Rezaie, A, Masoodi, A. M, Mehrzadi, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen Acetaminophen, deferoxamine, hepatotoxicity, rat, vanadium Animals Antioxidants Deferoxamine Dosage and administration Drug therapy Liver diseases Oxidative stress Properties Rodents Studies Toxicity Vanadium
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