Her2-specific Multivalent Adapters Confer Designed Tropism to Adenovirus for Gene Targeting

Adenoviruses (Ads) hold great promise as gene vectors for diagnostic or therapeutic applications. The native tropism of Ads must be modified to achieve disease site-specific gene delivery by Ad vectors and this should be done in a programmable way and with technology that can realistically be scaled...

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Veröffentlicht in:Journal of molecular biology 2011-01, Vol.405 (2), p.410-426
Hauptverfasser: Dreier, Birgit, Mikheeva, Galina, Belousova, Natalya, Parizek, Petra, Boczek, Edgar, Jelesarov, Ilian, Forrer, Patrik, Plückthun, Andreas, Krasnykh, Victor
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Sprache:eng
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