Emerging roles of JAK–STAT signaling pathways in adipocytes

Twenty years ago, adipocytes were largely considered to be inert energy-storage depots. We now know that fat cells are highly insulin-sensitive with significant endocrine functions. Alterations in adipocyte development or function can contribute to metabolic disease, in particular type 2 diabetes. T...

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Veröffentlicht in:	Trends in endocrinology and metabolism 2011-08, Vol.22 (8), p.325-332
Hauptverfasser:	Richard, Allison J, Stephens, Jacqueline M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - metabolism Animals Biological and medical sciences Endocrinology & Metabolism Fundamental and applied biological sciences. Psychology Humans Janus Kinases - genetics Janus Kinases - metabolism Models, Biological Signal Transduction - genetics Signal Transduction - physiology STAT Transcription Factors - genetics STAT Transcription Factors - metabolism Vertebrates: endocrinology
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