Role of angiotensin II receptor subtype activation in cognitive function and ischaemic brain damage

Recent clinical studies have demonstrated that angiotensin II type 1 (AT1) receptor blockers (ARBs) reduce the onset of stroke, stroke severity and the incidence and progression of Alzheimer's disease and dementia. We can expect that ARBs exert these effects by both AT1 receptor blockade and an...

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Veröffentlicht in:	British journal of pharmacology 2011-07, Vol.163 (6), p.1122-1130
Hauptverfasser:	Horiuchi, Masatsugu, Mogi, Masaki
Format:	Artikel
Sprache:	eng
Schlagworte:	angiotensin II Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Brain damage Brain Ischemia - metabolism Cardiology. Vascular system Cerebrum - blood supply Cerebrum - physiology Cognitive ability cognitive impairment Humans hypertension Medical research Medical sciences Neurology Pharmacology. Drug treatments receptor Receptor, Angiotensin, Type 1 - physiology Renin-Angiotensin System - physiology Reviews stroke Stroke - metabolism Vascular diseases and vascular malformations of the nervous system
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