Zinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantation

The critical trace element zinc is essential for normal insulin production, and plays a central role in cellular protection against apoptosis and oxidative stress. The regulation of zinc within the pancreas and β-cells is controlled by the zinc transporter families ZnT and ZIP. Pancreatic islets dis...

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Veröffentlicht in:	The review of diabetic studies 2010, Vol.7 (4), p.263-274
Hauptverfasser:	Bosco, Mariea D, Mohanasundaram, Daisy M, Drogemuller, Chris J, Lang, Carol J, Zalewski, Peter D, Coates, P Toby
Format:	Artikel
Sprache:	eng
Schlagworte:	Carrier Proteins - genetics Carrier Proteins - metabolism Diabetes Mellitus, Type 1 - metabolism Diabetes Mellitus, Type 1 - therapy Humans Insulin - metabolism Islets of Langerhans - cytology Islets of Langerhans - metabolism Islets of Langerhans Transplantation - methods Islets of Langerhans Transplantation - pathology Pancreas - metabolism Review Zinc - metabolism
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