Increased interleukin‐4‐positive lymphocytes in patients with Hashimoto's thyroiditis and concurrent non‐endocrine autoimmune disorders

Summary A prevalent T helper type 1 (Th1) subset of lymphocytes has been described in Hashimoto's thyroiditis (HT), but whether a similar polarization may characterize HT when associated with non‐endocrine autoimmune disorders (NEAD) is not known. The aim of the present study was to analyse the...

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Veröffentlicht in:	Clinical and experimental immunology 2011-08, Vol.165 (2), p.148-154
Hauptverfasser:	Santaguida, M. G., Nardo, S., Del Duca, S. C., Lococo, E., Virili, C., Gargano, L., Lenti, L., Centanni, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analytical, structural and metabolic biochemistry Autoimmune Diseases - complications Autoimmune Diseases - diagnosis autoimmune thyroiditis Biological and medical sciences cytokines Cytokines - blood Diagnosis, Differential Endocrinopathies Female Flow Cytometry Fundamental and applied biological sciences. Psychology Hashimoto Disease - complications Hashimoto Disease - diagnosis Hashimoto Disease - immunology Humans Interferon-gamma - biosynthesis Interleukin-2 - analysis Interleukin-4 - analysis interleukin‐4 Lymphocyte Count Male Medical sciences Middle Aged Non tumoral diseases. Target tissue resistance. Benign neoplasms PAS III Polyendocrinopathies, Autoimmune - complications Polyendocrinopathies, Autoimmune - diagnosis Th1 Cells - immunology Th1 lymphocytes Th2 Cells - immunology Th2 lymphocytes Thyroid. Thyroid axis (diseases) Translational Studies
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