The membrane-bound transcription factor CREB3L1 is activated in response to virus infection to inhibit proliferation of virus-infected cells

CREB3L1/OASIS is a cellular transcription factor synthesized as a membrane-bound precursor and activated by regulated intramembrane proteolysis in response to stimuli like ER stress. Comparing gene expression between Huh7 subclones that are permissive for hepatitis C virus (HCV) replication versus t...

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Veröffentlicht in:	Cell host & microbe 2011-07, Vol.10 (1), p.65-74
Hauptverfasser:	Denard, Bray, Seemann, Joachim, Chen, Qiuyue, Gay, Austin, Huang, Hua, Chen, Yan, Ye, Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Cell Nucleus - metabolism Cell Proliferation Cyclic AMP Response Element-Binding Protein - genetics Cyclic AMP Response Element-Binding Protein - metabolism Hepacivirus - pathogenicity Hepacivirus - physiology Hepatocytes - virology Host-Pathogen Interactions Humans Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Replicon Rhadinovirus - pathogenicity Sendai virus - pathogenicity Virus Replication West Nile virus - pathogenicity
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