Expression of NF-kappaB and IkappaB proteins in skeletal muscle of gastric cancer patients

The mechanisms eliciting cancer cachexia are not well understood. Wasting of skeletal muscle is problematic because it is responsible for the clinical deterioration in cancer patients and for the ability to tolerate cancer treatment. Studies done on animals suggest that nuclear factor of kappa B (NF...

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Veröffentlicht in:	European journal of cancer (1990) 2010-01, Vol.46 (1), p.191-197
Hauptverfasser:	Rhoads, Mary G, Kandarian, Susan C, Pacelli, Fabio, Doglietto, Giovan Battista, Bossola, Maurizio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cachexia - etiology Cachexia - metabolism Female Humans I-kappa B Proteins - metabolism Male Middle Aged Muscle, Skeletal - metabolism Neoplasm Proteins - metabolism Neoplasm Staging NF-kappa B - metabolism NF-KappaB Inhibitor alpha Nuclear Proteins - metabolism Nutrition Assessment Proto-Oncogene Proteins - metabolism Signal Transduction Stomach Neoplasms - complications Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Transcription Factors - metabolism
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