Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine
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| Veröffentlicht in: | Infection and Immunity 1990-11, Vol.58 (11), p.3653-3662 |
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| container_title | Infection and Immunity |
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| creator | LOOSMORE, S. M ZEALEY, G. R KLEIN, M. H BOUX, H. A COCKLE, S. A RADIKA, K FAHIM, R. E. F ZOBRIST, G. J YACOOB, R. K CHONG, P. C.-S FEI-LONG YAO |
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| doi_str_mv | 10.1128/IAI.58.11.3653-3662.1990 |
| format | Article |
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Print ISSN:
0019-9567
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</description><identifier>ISSN: 0019-9567</identifier><identifier>EISSN: 1098-5522</identifier><identifier>DOI: 10.1128/IAI.58.11.3653-3662.1990</identifier><identifier>PMID: 2228237</identifier><identifier>CODEN: INFIBR</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Amino Acid Sequence ; Animals ; Bacteriology ; Biological and medical sciences ; Cell Line ; Cloning, Molecular ; Cricetinae ; Cricetulus ; Female ; Fundamental and applied biological sciences. Psychology ; Gene Expression ; genetic engineering ; Mice ; Mice, Inbred Strains ; Microbiology ; Molecular Sequence Data ; Mutation ; Operon ; pertussis ; Pertussis Toxin ; Pertussis Vaccine ; Recombinant Proteins - genetics ; Recombinant Proteins - immunology ; site-directed mutagenesis ; toxins ; vaccines ; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies ; Vaccines, Synthetic ; Virulence Factors, Bordetella - biosynthesis ; Virulence Factors, Bordetella - genetics</subject><ispartof>Infection and Immunity, 1990-11, Vol.58 (11), p.3653-3662</ispartof><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c557t-10f857275af8e62f1d5b72f595dec5a83200576ab9a44edeb43ffce0af2fe2483</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC313711/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC313711/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,3188,3189,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19604372$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2228237$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LOOSMORE, S. M</creatorcontrib><creatorcontrib>ZEALEY, G. R</creatorcontrib><creatorcontrib>KLEIN, M. H</creatorcontrib><creatorcontrib>BOUX, H. A</creatorcontrib><creatorcontrib>COCKLE, S. A</creatorcontrib><creatorcontrib>RADIKA, K</creatorcontrib><creatorcontrib>FAHIM, R. E. F</creatorcontrib><creatorcontrib>ZOBRIST, G. J</creatorcontrib><creatorcontrib>YACOOB, R. K</creatorcontrib><creatorcontrib>CHONG, P. C.-S</creatorcontrib><creatorcontrib>FEI-LONG YAO</creatorcontrib><title>Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine</title><title>Infection and Immunity</title><addtitle>Infect Immun</addtitle><description>Classifications
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</description><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Bacteriology</subject><subject>Biological and medical sciences</subject><subject>Cell Line</subject><subject>Cloning, Molecular</subject><subject>Cricetinae</subject><subject>Cricetulus</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gene Expression</subject><subject>genetic engineering</subject><subject>Mice</subject><subject>Mice, Inbred Strains</subject><subject>Microbiology</subject><subject>Molecular Sequence Data</subject><subject>Mutation</subject><subject>Operon</subject><subject>pertussis</subject><subject>Pertussis Toxin</subject><subject>Pertussis Vaccine</subject><subject>Recombinant Proteins - genetics</subject><subject>Recombinant Proteins - immunology</subject><subject>site-directed mutagenesis</subject><subject>toxins</subject><subject>vaccines</subject><subject>Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies</subject><subject>Vaccines, Synthetic</subject><subject>Virulence Factors, Bordetella - biosynthesis</subject><subject>Virulence Factors, Bordetella - genetics</subject><issn>0019-9567</issn><issn>1098-5522</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUctu1DAUtRCoDIVPQLKQYJfBjzhxFiyqqpSRKrGBteU414lRYgc7mdK_x-mMymPl63teVzoIYUr2lDL58XB12AuZ5z2vBC94VbE9bRryDO0oaWQhBGPP0Y4Q2hSNqOqX6FVKP_K3LEt5gS4YY5LxeofWG987DxCd73GwuAcPizN6HB9wB0v45ayDDs8QlzUll_C28lh7PYY-YRtiph1hDPMEftkcNI5gwtQ6r_Pifghh3rxNWPsBH7UxOe41emH1mODN-b1E3z_ffLv-Utx9vT1cX90VRoh6KSixUtSsFtpKqJilnWhrZkUjOjBCS84IEXWl20aXJXTQltxaA0RbZoGVkl-iTyffeW0n6Ew-MepRzdFNOj6ooJ36F_FuUH04Kk55TWnWfzjrY_i5QlrU5JKBcdQewpoUrSiV9JEoT0QTQ0oR7FMGJWprTLmcJWSe1daY2hpTW2NZ-vbvG5-E54oy_v6M65R7sVF749If_6YiJa9Z5r078QbXD_cugtJp-i-W_wYM5a-H</recordid><startdate>19901101</startdate><enddate>19901101</enddate><creator>LOOSMORE, S. M</creator><creator>ZEALEY, G. R</creator><creator>KLEIN, M. H</creator><creator>BOUX, H. A</creator><creator>COCKLE, S. A</creator><creator>RADIKA, K</creator><creator>FAHIM, R. E. F</creator><creator>ZOBRIST, G. J</creator><creator>YACOOB, R. K</creator><creator>CHONG, P. C.-S</creator><creator>FEI-LONG YAO</creator><general>American Society for Microbiology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QO</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>5PM</scope></search><sort><creationdate>19901101</creationdate><title>Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine</title><author>LOOSMORE, S. M ; ZEALEY, G. R ; KLEIN, M. H ; BOUX, H. A ; COCKLE, S. A ; RADIKA, K ; FAHIM, R. E. F ; ZOBRIST, G. J ; YACOOB, R. K ; CHONG, P. C.-S ; FEI-LONG YAO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c557t-10f857275af8e62f1d5b72f595dec5a83200576ab9a44edeb43ffce0af2fe2483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Amino Acid Sequence</topic><topic>Animals</topic><topic>Bacteriology</topic><topic>Biological and medical sciences</topic><topic>Cell Line</topic><topic>Cloning, Molecular</topic><topic>Cricetinae</topic><topic>Cricetulus</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gene Expression</topic><topic>genetic engineering</topic><topic>Mice</topic><topic>Mice, Inbred Strains</topic><topic>Microbiology</topic><topic>Molecular Sequence Data</topic><topic>Mutation</topic><topic>Operon</topic><topic>pertussis</topic><topic>Pertussis Toxin</topic><topic>Pertussis Vaccine</topic><topic>Recombinant Proteins - genetics</topic><topic>Recombinant Proteins - immunology</topic><topic>site-directed mutagenesis</topic><topic>toxins</topic><topic>vaccines</topic><topic>Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies</topic><topic>Vaccines, Synthetic</topic><topic>Virulence Factors, Bordetella - biosynthesis</topic><topic>Virulence Factors, Bordetella - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LOOSMORE, S. M</creatorcontrib><creatorcontrib>ZEALEY, G. R</creatorcontrib><creatorcontrib>KLEIN, M. H</creatorcontrib><creatorcontrib>BOUX, H. 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A</au><au>COCKLE, S. A</au><au>RADIKA, K</au><au>FAHIM, R. E. F</au><au>ZOBRIST, G. J</au><au>YACOOB, R. K</au><au>CHONG, P. C.-S</au><au>FEI-LONG YAO</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine</atitle><jtitle>Infection and Immunity</jtitle><addtitle>Infect Immun</addtitle><date>1990-11-01</date><risdate>1990</risdate><volume>58</volume><issue>11</issue><spage>3653</spage><epage>3662</epage><pages>3653-3662</pages><issn>0019-9567</issn><eissn>1098-5522</eissn><coden>INFIBR</coden><abstract>Classifications
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>2228237</pmid><doi>10.1128/IAI.58.11.3653-3662.1990</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0019-9567 |
| ispartof | Infection and Immunity, 1990-11, Vol.58 (11), p.3653-3662 |
| issn | 0019-9567 1098-5522 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_313711 |
| source | MEDLINE; American Society for Microbiology Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Amino Acid Sequence Animals Bacteriology Biological and medical sciences Cell Line Cloning, Molecular Cricetinae Cricetulus Female Fundamental and applied biological sciences. Psychology Gene Expression genetic engineering Mice Mice, Inbred Strains Microbiology Molecular Sequence Data Mutation Operon pertussis Pertussis Toxin Pertussis Vaccine Recombinant Proteins - genetics Recombinant Proteins - immunology site-directed mutagenesis toxins vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Vaccines, Synthetic Virulence Factors, Bordetella - biosynthesis Virulence Factors, Bordetella - genetics |
| title | Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine |
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