Risk of Chronic Beryllium Disease by HLA-DPB1 E69 Genotype and Beryllium Exposure in Nuclear Workers

Beryllium sensitization (BeS) and chronic beryllium disease (CBD) are determined by at least one genetic factor, a glutamic acid at position 69 (E69) of the HLA-DPB1 gene, and by exposure to beryllium. The relationship between exposure and the E69 genotype has not been well characterized. The study...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2011-06, Vol.183 (12), p.1680-1688
Hauptverfasser: VAN DYKE, Mike V, MARTYNY, John W, MROZ, Margaret M, SILVEIRA, Lori J, STRAND, Matt, FINGERLIN, Tasha E, SATO, Hiroe, NEWMAN, Lee S, MAIER, Lisa A
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Sprache:eng
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