RNA interference screen for human genes associated with West Nile virus infection

West Nile virus: interaction with human cells This manuscript reports a comprehensive systems level description of the molecular signatures governing the interaction of West Nile virus with human cells. A whole-genome human RNA interference gene silencing screen in HeLa cells identified 305 host pro...

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Veröffentlicht in:	Nature 2008-09, Vol.455 (7210), p.242-245
Hauptverfasser:	Krishnan, Manoj N., Ng, Aylwin, Sukumaran, Bindu, Gilfoy, Felicia D., Uchil, Pradeep D., Sultana, Hameeda, Brass, Abraham L., Adametz, Rachel, Tsui, Melody, Qian, Feng, Montgomery, Ruth R., Lev, Sima, Mason, Peter W., Koski, Raymond A., Elledge, Stephen J., Xavier, Ramnik J., Agaisse, Herve, Fikrig, Erol
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell adhesion & migration Changes Computational Biology Dengue virus Dengue Virus - physiology Endoplasmic Reticulum - metabolism Gene Expression Profiling Genes Genetic aspects Genome, Human HeLa Cells HIV Humanities and Social Sciences Humans Identification and classification Immunity - genetics Infectious diseases letter Medical sciences Monocarboxylic Acid Transporters - deficiency Monocarboxylic Acid Transporters - genetics Monocarboxylic Acid Transporters - metabolism multidisciplinary Muscle Proteins - deficiency Muscle Proteins - genetics Muscle Proteins - metabolism Protein Binding Proteins Ribonucleic acid RNA RNA Interference Science Science (multidisciplinary) Ubiquitin-Protein Ligases - deficiency Ubiquitin-Protein Ligases - genetics Ubiquitin-Protein Ligases - metabolism Ubiquitination - genetics Vector-borne diseases Vesiculovirus Viral diseases Viral proteins Virus Replication West Nile Fever - genetics West Nile Fever - virology West Nile virus West Nile virus - physiology
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