Mucin production during prenatal and postnatal murine lung development

Mucus is a protective gel that lines respiratory tract surfaces. To identify potential roles for secreted gel--forming mucins in lung development, we isolated murine lungs on embryonic days (E) 12.5-18.5, and postnatal days (PN) days 5, 14, and 28. We measured the mucin gene expression by quantitati...

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Veröffentlicht in:	American journal of respiratory cell and molecular biology 2011-06, Vol.44 (6), p.755-760
Hauptverfasser:	Roy, Michelle G, Rahmani, Mahdis, Hernandez, Jesus R, Alexander, Samantha N, Ehre, Camille, Ho, Samuel B, Evans, Christopher M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Female Gene Expression Regulation, Developmental Homeostasis Immunohistochemistry - methods Lung - embryology Lung - growth & development Lung - metabolism Mice Mice, Inbred C57BL Models, Biological Mucin 5AC - biosynthesis Mucin-5B - biosynthesis Mucins - metabolism Rapid Communications Reverse Transcriptase Polymerase Chain Reaction Time Factors
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