Effects of Histamine on Light Responses of Amacrine Cells in Tiger Salamander Retina
Using immunofluorescence, we showed that histamine receptor 1 is expressed by horizontal cell axons and a subset of amacrine cells in the tiger salamander retina. The effects of histamine on light responses of amacrine cells were studied in slice preparations. Histamine modulated the light responses...
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| Veröffentlicht in: | Neurochemical research 2011-04, Vol.36 (4), p.645-654 |
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| creator | Yu, Yongchun Satoh, Hiromasa Vila, Alejandro Wu, Samuel M. Marshak, David W. |
| description | Using immunofluorescence, we showed that histamine receptor 1 is expressed by horizontal cell axons and a subset of amacrine cells in the tiger salamander retina. The effects of histamine on light responses of amacrine cells were studied in slice preparations. Histamine modulated the light responses of many salamander amacrine cells, depending upon the morphological type. The most pronounced effects of histamine were decreases in the light responses of broadly stratified amacrine cells, particularly those having medium-sized dendritic field diameters. To determine whether the effects of histamine were direct, Co
++
was substituted for Ca
++
in the extracellular medium to block synaptic transmission. Histamine still affected broadly stratified amacrine cells, but not narrowly stratified amacrine cells under these conditions. Taken together, these findings suggest that inhibitory interactions between strata of the IPL and within the classical receptive fields of the ganglion cells would be particularly sensitive to histamine released from retinopetal axons. |
| doi_str_mv | 10.1007/s11064-010-0278-0 |
| format | Article |
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++
was substituted for Ca
++
in the extracellular medium to block synaptic transmission. Histamine still affected broadly stratified amacrine cells, but not narrowly stratified amacrine cells under these conditions. Taken together, these findings suggest that inhibitory interactions between strata of the IPL and within the classical receptive fields of the ganglion cells would be particularly sensitive to histamine released from retinopetal axons.</description><identifier>ISSN: 0364-3190</identifier><identifier>EISSN: 1573-6903</identifier><identifier>DOI: 10.1007/s11064-010-0278-0</identifier><identifier>PMID: 20878231</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Amacrine Cells - physiology ; Ambystoma tigrinum ; Animals ; Biochemistry ; Biomedical and Life Sciences ; Biomedicine ; Caudata ; Cell Biology ; Fluorescent Antibody Technique ; Histamine - physiology ; Light ; Membrane Potentials ; Neurochemistry ; Neurology ; Neurosciences ; Original Paper ; Retina - cytology ; Retina - physiology ; Urodela</subject><ispartof>Neurochemical research, 2011-04, Vol.36 (4), p.645-654</ispartof><rights>Springer Science+Business Media, LLC 2010</rights><rights>Springer Science+Business Media, LLC 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c532t-8623883e66942adf55e17b82d0c81053ecc2db3815e08b060721e3c6e8b857c23</citedby><cites>FETCH-LOGICAL-c532t-8623883e66942adf55e17b82d0c81053ecc2db3815e08b060721e3c6e8b857c23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11064-010-0278-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11064-010-0278-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,776,780,881,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20878231$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yu, Yongchun</creatorcontrib><creatorcontrib>Satoh, Hiromasa</creatorcontrib><creatorcontrib>Vila, Alejandro</creatorcontrib><creatorcontrib>Wu, Samuel M.</creatorcontrib><creatorcontrib>Marshak, David W.</creatorcontrib><title>Effects of Histamine on Light Responses of Amacrine Cells in Tiger Salamander Retina</title><title>Neurochemical research</title><addtitle>Neurochem Res</addtitle><addtitle>Neurochem Res</addtitle><description>Using immunofluorescence, we showed that histamine receptor 1 is expressed by horizontal cell axons and a subset of amacrine cells in the tiger salamander retina. The effects of histamine on light responses of amacrine cells were studied in slice preparations. Histamine modulated the light responses of many salamander amacrine cells, depending upon the morphological type. The most pronounced effects of histamine were decreases in the light responses of broadly stratified amacrine cells, particularly those having medium-sized dendritic field diameters. To determine whether the effects of histamine were direct, Co
++
was substituted for Ca
++
in the extracellular medium to block synaptic transmission. Histamine still affected broadly stratified amacrine cells, but not narrowly stratified amacrine cells under these conditions. Taken together, these findings suggest that inhibitory interactions between strata of the IPL and within the classical receptive fields of the ganglion cells would be particularly sensitive to histamine released from retinopetal axons.</description><subject>Amacrine Cells - physiology</subject><subject>Ambystoma tigrinum</subject><subject>Animals</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Caudata</subject><subject>Cell Biology</subject><subject>Fluorescent Antibody Technique</subject><subject>Histamine - physiology</subject><subject>Light</subject><subject>Membrane Potentials</subject><subject>Neurochemistry</subject><subject>Neurology</subject><subject>Neurosciences</subject><subject>Original Paper</subject><subject>Retina - cytology</subject><subject>Retina - physiology</subject><subject>Urodela</subject><issn>0364-3190</issn><issn>1573-6903</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkk1rFEEQhhtRzBr9AV5k8OJptKp7-2MuQlhiIiwIcT03PT01mw4zPWv3bMB_b282xg-QnLrgfeptqt5i7DXCewTQHzIiqGUNCDVwbWp4whYotahVA-IpW4AoqsAGTtiLnG-ggMDxOTvhYLThAhdsc9735OdcTX11GfLsxhCpmmK1DtvrubqivJtipjv9bHQ-HeQVDUOuQqw2YUup-uoGN7rYlfKK5hDdS_asd0OmV_fvKfv26XyzuqzXXy4-r87WtZeCz7VRXBgjSKlmyV3XS0moW8M78AZBCvKed60wKAlMCwo0RxJekWmN1J6LU_bx6LvbtyN1nuKc3GB3KYwu_bCTC_ZvJYZru51urUAhBehi8O7eIE3f95RnO4bsy3Qu0rTPtgEulIYlf5Q0eomNkKgeJ6XhRmtpCvn2H_Jm2qdYNlYg3TRK8QOER8inKedE_cN4CPZwBfZ4BbaEaw9XYKH0vPlzLw8dv2IvAD8CuUixZPj75_-7_gTX67sV</recordid><startdate>20110401</startdate><enddate>20110401</enddate><creator>Yu, Yongchun</creator><creator>Satoh, Hiromasa</creator><creator>Vila, Alejandro</creator><creator>Wu, Samuel M.</creator><creator>Marshak, David W.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QR</scope><scope>7TK</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>F1W</scope><scope>H95</scope><scope>L.G</scope><scope>5PM</scope></search><sort><creationdate>20110401</creationdate><title>Effects of Histamine on Light Responses of Amacrine Cells in Tiger Salamander Retina</title><author>Yu, Yongchun ; Satoh, Hiromasa ; Vila, Alejandro ; Wu, Samuel M. ; Marshak, David W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c532t-8623883e66942adf55e17b82d0c81053ecc2db3815e08b060721e3c6e8b857c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Amacrine Cells - physiology</topic><topic>Ambystoma tigrinum</topic><topic>Animals</topic><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Caudata</topic><topic>Cell Biology</topic><topic>Fluorescent Antibody Technique</topic><topic>Histamine - physiology</topic><topic>Light</topic><topic>Membrane Potentials</topic><topic>Neurochemistry</topic><topic>Neurology</topic><topic>Neurosciences</topic><topic>Original Paper</topic><topic>Retina - cytology</topic><topic>Retina - physiology</topic><topic>Urodela</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yu, Yongchun</creatorcontrib><creatorcontrib>Satoh, Hiromasa</creatorcontrib><creatorcontrib>Vila, Alejandro</creatorcontrib><creatorcontrib>Wu, Samuel M.</creatorcontrib><creatorcontrib>Marshak, David W.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Neurochemical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yu, Yongchun</au><au>Satoh, Hiromasa</au><au>Vila, Alejandro</au><au>Wu, Samuel M.</au><au>Marshak, David W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of Histamine on Light Responses of Amacrine Cells in Tiger Salamander Retina</atitle><jtitle>Neurochemical research</jtitle><stitle>Neurochem Res</stitle><addtitle>Neurochem Res</addtitle><date>2011-04-01</date><risdate>2011</risdate><volume>36</volume><issue>4</issue><spage>645</spage><epage>654</epage><pages>645-654</pages><issn>0364-3190</issn><eissn>1573-6903</eissn><abstract>Using immunofluorescence, we showed that histamine receptor 1 is expressed by horizontal cell axons and a subset of amacrine cells in the tiger salamander retina. 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++
was substituted for Ca
++
in the extracellular medium to block synaptic transmission. Histamine still affected broadly stratified amacrine cells, but not narrowly stratified amacrine cells under these conditions. Taken together, these findings suggest that inhibitory interactions between strata of the IPL and within the classical receptive fields of the ganglion cells would be particularly sensitive to histamine released from retinopetal axons.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>20878231</pmid><doi>10.1007/s11064-010-0278-0</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Amacrine Cells - physiology Ambystoma tigrinum Animals Biochemistry Biomedical and Life Sciences Biomedicine Caudata Cell Biology Fluorescent Antibody Technique Histamine - physiology Light Membrane Potentials Neurochemistry Neurology Neurosciences Original Paper Retina - cytology Retina - physiology Urodela |
| title | Effects of Histamine on Light Responses of Amacrine Cells in Tiger Salamander Retina |
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