Polymorph Transformation in Paracetamol Monitored by In-line NIR Spectroscopy During a Cooling Crystallization Process

The reliable in-line monitoring of pharmaceutical processes has been regarded as a key tool toward the full implementation of process analytical technology. In this study, near-infrared (NIR) spectroscopy was examined for use as an in-line monitoring method of the paracetamol cooling crystallization...

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Veröffentlicht in:AAPS PharmSciTech 2011-06, Vol.12 (2), p.764-770
Hauptverfasser: Wang, In-Chun, Lee, Min-Jeong, Seo, Da-Young, Lee, Hea-Eun, Choi, Yongsun, Kim, Woo-Sik, Kim, Chang-Sam, Jeong, Myung-Yung, Choi, Guang Jin
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Sprache:eng
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