Mice lacking brain-type creatine kinase activity show defective thermoregulation

Abstract The cytosolic brain-type creatine kinase and mitochondrial ubiquitous creatine kinase (CK-B and UbCKmit) are expressed during the prepubescent and adult period of mammalian life. These creatine kinase (CK) isoforms are present in neural cell types throughout the central and peripheral nervo...

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Veröffentlicht in:	Physiology & behavior 2009-04, Vol.97 (1), p.76-86
Hauptverfasser:	Streijger, Femke, Pluk, Helma, Oerlemans, Frank, Beckers, Gaby, Bianco, Antonio C, Ribeiro, Miriam O, Wieringa, Bé, Van der Zee, Catharina E.E.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - cytology Adipocytes - ultrastructure Adipose Tissue, Brown - drug effects Adipose Tissue, Brown - metabolism Adipose Tissue, White - metabolism Animals Behavioral psychophysiology Biological and medical sciences Blood Glucose Body Temperature Regulation - physiology Brown adipose tissue Circadian Rhythm Creatine kinase Creatine kinase double knockout mice Creatine Kinase, BB Form - genetics Creatine Kinase, BB Form - physiology Creatine Kinase, Mitochondrial Form - genetics Creatine Kinase, Mitochondrial Form - physiology Eating - physiology Energy Metabolism - physiology Fundamental and applied biological sciences. Psychology Ion Channels - metabolism Leptin - blood Lipids - blood Male Mice Mice, Inbred Strains Mice, Knockout Mitochondrial Proteins - metabolism Motor Activity Norepinephrine - pharmacology Organ Size Psychiatry Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Stress, Physiological Thermogenic activity UCP1 mRNA Uncoupling Protein 1 White adipose tissue
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