Molecular profiles of EGFR, K-ras, c-met, and FGFR in pulmonary pleomorphic carcinoma, a rare lung malignancy

Background Pulmonary pleomorphic carcinoma (PPC) is a rare type of lung cancer characterized by the poor response to conventional chemotherapy and subsequent disappointing outcomes. Therefore, it is paramount to delineate the molecular characteristics of this disease entity. Methods In this study, w...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2011-08, Vol.137 (8), p.1203-1211
Hauptverfasser:	Lee, Soohyeon, Kim, Youngwook, Sun, Jong-Mu, Choi, Yoon La, Kim, Jhin Gook, Shim, Young-Mog, Park, Yeon Hee, Ahn, Jin Seok, Park, Keunchil, Han, Jung Ho, Ahn, Myung-Ju
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Analysis of Variance Antineoplastic agents Biological and medical sciences Biomarkers, Tumor - genetics Cancer Research Carcinoma - genetics Carcinoma - pathology Carcinoma - surgery Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - pathology Female Hematology Humans In Situ Hybridization, Fluorescence Internal Medicine Lung cancer Lung Neoplasms - genetics Lung Neoplasms - pathology Lung Neoplasms - surgery Male Medical sciences Medicine Medicine & Public Health Middle Aged Molecular biology Mutation Oncology Original Paper Pathology Pharmacology. Drug treatments Pneumology Polymerase Chain Reaction Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins c-met - genetics Proto-Oncogene Proteins p21(ras) Rare Diseases - genetics ras Proteins - genetics Receptor, Epidermal Growth Factor - genetics Receptors, Fibroblast Growth Factor - genetics Retrospective Studies Sequence Analysis, DNA Tumors of the respiratory system and mediastinum
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