Enhanced contact allergen- and UVB-induced keratinocyte apoptosis in the absence of CD95/Fas/Apo-1

FAS/CD95/Apo-1 is a ubiquitously expressed cell-surface receptor involved in the initiation of programmed cell death. Its function in epidermal keratinocytes has been incompletely defined. Available evidence from in vitro studies points to important roles of Fas in the pathogenesis of contact dermat...

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Veröffentlicht in:	Cell death and differentiation 2011-01, Vol.18 (1), p.155-163
Hauptverfasser:	Hedrych-Ozimina, A, Behrendt, K, Hao, Z, Pofahl, R, Ussath, D, Knaup, R, Krieg, T, Haase, I
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/249/2510/9 631/80/82/23 692/1807/1812 Allergens Animals Apoptosis Biochemistry Biomedical and Life Sciences CD95 antigen Cell Biology Cell Cycle Analysis Cell death Contact dermatitis Dermatitis Dermatitis, Contact - etiology Dermatitis, Contact - pathology Dermatology Dinitrofluorobenzene DNA damage Epidermal growth factor Epidermis Fas antigen fas Receptor - genetics fas Receptor - metabolism fas Receptor - physiology Gene deletion Keratinocytes Keratinocytes - pathology Keratinocytes - radiation effects Kinases Life Sciences Ligands Light Light effects Lymphocytes Mice Mice, Knockout Original Paper Pathogenesis Skin Stem Cells Tumor necrosis factor-TNF U.V. radiation Ultraviolet radiation Ultraviolet Rays
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