Engineering ligand-responsive RNA controllers in yeast through the assembly of RNase III tuning modules

The programming of cellular networks to achieve new biological functions depends on the development of genetic tools that link the presence of a molecular signal to gene-regulatory activity. Recently, a set of engineered RNA controllers was described that enabled predictable tuning of gene expressio...

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Veröffentlicht in:	Nucleic acids research 2011-07, Vol.39 (12), p.5299-5311
Hauptverfasser:	Babiskin, Andrew H., Smolke, Christina D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aptamers, Nucleotide - chemistry Aptamers, Nucleotide - metabolism Gene Expression Regulation Genetic Engineering Ligands Ribonuclease III - metabolism Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins - metabolism Synthetic Biology and Chemistry Theophylline - pharmacology
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