The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle

The mammalian Cutl1 gene codes for the CCAAT displacement protein (CDP), which has been implicated as a transcriptional repressor in diverse processes such as terminal differentiation, cell cycle progression, and the control of nuclear matrix attachment regions. To investigate the in vivo function o...

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Veröffentlicht in:	Genes & development 2001-09, Vol.15 (17), p.2307-2319
Hauptverfasser:	Ellis, T, Gambardella, L, Horcher, M, Tschanz, S, Capol, J, Bertram, P, Jochum, W, Barrandon, Y, Busslinger, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals beta-Galactosidase - metabolism CCAAT displacement protein Cell Differentiation Cut protein Cutl1 gene Cytoplasm - metabolism DNA, Complementary - metabolism Drosophila Epithelial Cells - metabolism Exons Gene Expression Regulation, Developmental Hair - embryology Hedgehog Proteins Homeodomain Proteins Immunohistochemistry In Situ Hybridization lacZ gene Lung - cytology Lung - embryology Lung - pathology Mice Models, Genetic Molecular Sequence Data Mutagenesis, Site-Directed Mutation Nuclear Proteins - physiology Protein Structure, Tertiary Repressor Proteins - physiology Research Paper Sonic hedgehog gene Time Factors Trans-Activators - metabolism Transcription, Genetic Transfection
Online-Zugang:	Volltext
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