Individual variations in inorganic arsenic metabolism associated with AS3MT genetic polymorphisms

Individual variations in inorganic arsenic metabolism may influence the toxic effects. Arsenic (+3 oxidation state) methyltransferase (AS3MT) that can catalyze the transfer of a methyl group from S-adenosyl-l-methionine (AdoMet) to trivalent arsenical, may play a role in arsenic metabolism in humans...

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Veröffentlicht in:	International journal of molecular sciences 2011-04, Vol.12 (4), p.2351-2382
Hauptverfasser:	Agusa, Tetsuro, Fujihara, Junko, Takeshita, Haruo, Iwata, Hisato
Format:	Artikel
Sprache:	eng
Schlagworte:	Arsenic - metabolism Gene Frequency Humans Methylation Methyltransferases - genetics Polymorphism, Single Nucleotide Racial Groups - genetics Review S-Adenosylmethionine - chemistry S-Adenosylmethionine - metabolism
Online-Zugang:	Volltext
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