Evaluating Translational Research: A Process Marker Model

Objective: We examine the concept of translational research from the perspective of evaluators charged with assessing translational efforts. One of the major tasks for evaluators involved in translational research is to help assess efforts that aim to reduce the time it takes to move research to pra...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clinical and translational science 2011-06, Vol.4 (3), p.153-162
Hauptverfasser: Trochim, William, Kane, Cathleen, Graham, Mark J., Pincus, Harold A.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 162
container_issue 3
container_start_page 153
container_title Clinical and translational science
container_volume 4
creator Trochim, William
Kane, Cathleen
Graham, Mark J.
Pincus, Harold A.
description Objective: We examine the concept of translational research from the perspective of evaluators charged with assessing translational efforts. One of the major tasks for evaluators involved in translational research is to help assess efforts that aim to reduce the time it takes to move research to practice and health impacts. Another is to assess efforts that are intended to increase the rate and volume of translation. Methods: We offer an alternative to the dominant contemporary tendency to define translational research in terms of a series of discrete “phases.”Results: We contend that this phased approach has been confusing and that it is insufficient as a basis for evaluation. Instead, we argue for the identification of key operational and measurable markers along a generalized process pathway from research to practice. Conclusions: This model provides a foundation for the evaluation of interventions designed to improve translational research and the integration of these findings into a field of translational studies. Clin Trans Sci 2011; Volume 4: 153–162
doi_str_mv 10.1111/j.1752-8062.2011.00291.x
format Article
fullrecord <record><control><sourceid>proquest_24P</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3125608</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>883854092</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5651-9047f65ececa0dc50b1403f051d9cc5de98112fe9a0e551e702c2a36a541047e3</originalsourceid><addsrcrecordid>eNqNkU9P3DAQxa0KVP71K1S59ZQwdmInqSoklNIFCVrELuI4Ms4EsvUmYO_C8u3xshDBDV_8pHnvjfUzYxGHhIezP014LkVcgBKJAM4TAFHyZPmFbQ-DjUHLbIvteD8FUKkq5Fe2JXgOeZll26w8etB2oedtdxNNnO68DbrvtI0uyJN25vZndBidu96Q99GZdv_JRWd9TXaPbTbaevr2eu-yyz9Hk-o4Pv03OqkOT2MjleRxCVneKEmGjIbaSLjmGaQNSF6XxsiayoJz0VCpgaTklIMwQqdKy4yHKKW77GDde7e4nlFtqJs7bfHOtTPtnrDXLX6cdO0t3vQPmHIhFRSh4MdrgevvF-TnOGu9IWt1R_3CY1GkhcygFMFZrJ3G9d47aoYtHHAFHqe4YoorvrgCjy_gcRmi39-_cgi-kQ6GX2vDY2vp6dPFWE3GQYR4vI63fk7LIR7-A1We5hKv_o7wt6quYFSNcZw-A70LoHM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>883854092</pqid></control><display><type>article</type><title>Evaluating Translational Research: A Process Marker Model</title><source>Wiley Online Library Open Access</source><creator>Trochim, William ; Kane, Cathleen ; Graham, Mark J. ; Pincus, Harold A.</creator><creatorcontrib>Trochim, William ; Kane, Cathleen ; Graham, Mark J. ; Pincus, Harold A.</creatorcontrib><description>Objective: We examine the concept of translational research from the perspective of evaluators charged with assessing translational efforts. One of the major tasks for evaluators involved in translational research is to help assess efforts that aim to reduce the time it takes to move research to practice and health impacts. Another is to assess efforts that are intended to increase the rate and volume of translation. Methods: We offer an alternative to the dominant contemporary tendency to define translational research in terms of a series of discrete “phases.”Results: We contend that this phased approach has been confusing and that it is insufficient as a basis for evaluation. Instead, we argue for the identification of key operational and measurable markers along a generalized process pathway from research to practice. Conclusions: This model provides a foundation for the evaluation of interventions designed to improve translational research and the integration of these findings into a field of translational studies. Clin Trans Sci 2011; Volume 4: 153–162</description><identifier>ISSN: 1752-8054</identifier><identifier>EISSN: 1752-8062</identifier><identifier>DOI: 10.1111/j.1752-8062.2011.00291.x</identifier><identifier>PMID: 21707944</identifier><language>eng</language><publisher>Malden, USA: Blackwell Publishing Inc</publisher><subject>Biomedical Research - trends ; clinical trials ; Clinical Trials as Topic ; Diffusion of Innovation ; evaluation ; Evidence-Based Medicine - organization &amp; administration ; Humans ; Models, Theoretical ; Outcome and Process Assessment (Health Care) - organization &amp; administration ; process modeling ; Translational Medical Research - standards ; Translational Medical Research - trends ; translational research</subject><ispartof>Clinical and translational science, 2011-06, Vol.4 (3), p.153-162</ispartof><rights>2011 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5651-9047f65ececa0dc50b1403f051d9cc5de98112fe9a0e551e702c2a36a541047e3</citedby><cites>FETCH-LOGICAL-c5651-9047f65ececa0dc50b1403f051d9cc5de98112fe9a0e551e702c2a36a541047e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125608/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125608/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,725,778,782,883,1414,11545,27907,27908,45557,45558,46035,46459,53774,53776</link.rule.ids><linktorsrc>$$Uhttps://onlinelibrary.wiley.com/doi/abs/10.1111%2Fj.1752-8062.2011.00291.x$$EView_record_in_Wiley-Blackwell$$FView_record_in_$$GWiley-Blackwell</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21707944$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Trochim, William</creatorcontrib><creatorcontrib>Kane, Cathleen</creatorcontrib><creatorcontrib>Graham, Mark J.</creatorcontrib><creatorcontrib>Pincus, Harold A.</creatorcontrib><title>Evaluating Translational Research: A Process Marker Model</title><title>Clinical and translational science</title><addtitle>Clin Transl Sci</addtitle><description>Objective: We examine the concept of translational research from the perspective of evaluators charged with assessing translational efforts. One of the major tasks for evaluators involved in translational research is to help assess efforts that aim to reduce the time it takes to move research to practice and health impacts. Another is to assess efforts that are intended to increase the rate and volume of translation. Methods: We offer an alternative to the dominant contemporary tendency to define translational research in terms of a series of discrete “phases.”Results: We contend that this phased approach has been confusing and that it is insufficient as a basis for evaluation. Instead, we argue for the identification of key operational and measurable markers along a generalized process pathway from research to practice. Conclusions: This model provides a foundation for the evaluation of interventions designed to improve translational research and the integration of these findings into a field of translational studies. Clin Trans Sci 2011; Volume 4: 153–162</description><subject>Biomedical Research - trends</subject><subject>clinical trials</subject><subject>Clinical Trials as Topic</subject><subject>Diffusion of Innovation</subject><subject>evaluation</subject><subject>Evidence-Based Medicine - organization &amp; administration</subject><subject>Humans</subject><subject>Models, Theoretical</subject><subject>Outcome and Process Assessment (Health Care) - organization &amp; administration</subject><subject>process modeling</subject><subject>Translational Medical Research - standards</subject><subject>Translational Medical Research - trends</subject><subject>translational research</subject><issn>1752-8054</issn><issn>1752-8062</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU9P3DAQxa0KVP71K1S59ZQwdmInqSoklNIFCVrELuI4Ms4EsvUmYO_C8u3xshDBDV_8pHnvjfUzYxGHhIezP014LkVcgBKJAM4TAFHyZPmFbQ-DjUHLbIvteD8FUKkq5Fe2JXgOeZll26w8etB2oedtdxNNnO68DbrvtI0uyJN25vZndBidu96Q99GZdv_JRWd9TXaPbTbaevr2eu-yyz9Hk-o4Pv03OqkOT2MjleRxCVneKEmGjIbaSLjmGaQNSF6XxsiayoJz0VCpgaTklIMwQqdKy4yHKKW77GDde7e4nlFtqJs7bfHOtTPtnrDXLX6cdO0t3vQPmHIhFRSh4MdrgevvF-TnOGu9IWt1R_3CY1GkhcygFMFZrJ3G9d47aoYtHHAFHqe4YoorvrgCjy_gcRmi39-_cgi-kQ6GX2vDY2vp6dPFWE3GQYR4vI63fk7LIR7-A1We5hKv_o7wt6quYFSNcZw-A70LoHM</recordid><startdate>201106</startdate><enddate>201106</enddate><creator>Trochim, William</creator><creator>Kane, Cathleen</creator><creator>Graham, Mark J.</creator><creator>Pincus, Harold A.</creator><general>Blackwell Publishing Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201106</creationdate><title>Evaluating Translational Research: A Process Marker Model</title><author>Trochim, William ; Kane, Cathleen ; Graham, Mark J. ; Pincus, Harold A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5651-9047f65ececa0dc50b1403f051d9cc5de98112fe9a0e551e702c2a36a541047e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Biomedical Research - trends</topic><topic>clinical trials</topic><topic>Clinical Trials as Topic</topic><topic>Diffusion of Innovation</topic><topic>evaluation</topic><topic>Evidence-Based Medicine - organization &amp; administration</topic><topic>Humans</topic><topic>Models, Theoretical</topic><topic>Outcome and Process Assessment (Health Care) - organization &amp; administration</topic><topic>process modeling</topic><topic>Translational Medical Research - standards</topic><topic>Translational Medical Research - trends</topic><topic>translational research</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Trochim, William</creatorcontrib><creatorcontrib>Kane, Cathleen</creatorcontrib><creatorcontrib>Graham, Mark J.</creatorcontrib><creatorcontrib>Pincus, Harold A.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Clinical and translational science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Trochim, William</au><au>Kane, Cathleen</au><au>Graham, Mark J.</au><au>Pincus, Harold A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluating Translational Research: A Process Marker Model</atitle><jtitle>Clinical and translational science</jtitle><addtitle>Clin Transl Sci</addtitle><date>2011-06</date><risdate>2011</risdate><volume>4</volume><issue>3</issue><spage>153</spage><epage>162</epage><pages>153-162</pages><issn>1752-8054</issn><eissn>1752-8062</eissn><abstract>Objective: We examine the concept of translational research from the perspective of evaluators charged with assessing translational efforts. One of the major tasks for evaluators involved in translational research is to help assess efforts that aim to reduce the time it takes to move research to practice and health impacts. Another is to assess efforts that are intended to increase the rate and volume of translation. Methods: We offer an alternative to the dominant contemporary tendency to define translational research in terms of a series of discrete “phases.”Results: We contend that this phased approach has been confusing and that it is insufficient as a basis for evaluation. Instead, we argue for the identification of key operational and measurable markers along a generalized process pathway from research to practice. Conclusions: This model provides a foundation for the evaluation of interventions designed to improve translational research and the integration of these findings into a field of translational studies. Clin Trans Sci 2011; Volume 4: 153–162</abstract><cop>Malden, USA</cop><pub>Blackwell Publishing Inc</pub><pmid>21707944</pmid><doi>10.1111/j.1752-8062.2011.00291.x</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier ISSN: 1752-8054
ispartof Clinical and translational science, 2011-06, Vol.4 (3), p.153-162
issn 1752-8054
1752-8062
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3125608
source Wiley Online Library Open Access
subjects Biomedical Research - trends
clinical trials
Clinical Trials as Topic
Diffusion of Innovation
evaluation
Evidence-Based Medicine - organization & administration
Humans
Models, Theoretical
Outcome and Process Assessment (Health Care) - organization & administration
process modeling
Translational Medical Research - standards
Translational Medical Research - trends
translational research
title Evaluating Translational Research: A Process Marker Model
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T00%3A48%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_24P&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Evaluating%20Translational%20Research:%20A%20Process%20Marker%20Model&rft.jtitle=Clinical%20and%20translational%20science&rft.au=Trochim,%20William&rft.date=2011-06&rft.volume=4&rft.issue=3&rft.spage=153&rft.epage=162&rft.pages=153-162&rft.issn=1752-8054&rft.eissn=1752-8062&rft_id=info:doi/10.1111/j.1752-8062.2011.00291.x&rft_dat=%3Cproquest_24P%3E883854092%3C/proquest_24P%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=883854092&rft_id=info:pmid/21707944&rfr_iscdi=true