Effects of the Topical Application of Hydroalcoholic Leaf Extract of Oncidium flexuosum Sims. (Orchidaceae) and Microcurrent on the Healing of Wounds Surgically Induced in Wistar Rats

This study evaluated the wound healing activity of hydroalcoholic leaf extract of Oncidium flexuosum Sims. (Orchidaceae), an important native plant of Brazil, combined or not with microcurrent stimulation. Wistar rats were randomly divided into four groups of nine animals: control (C), topical appli...

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Veröffentlicht in:Evidence-based complementary and alternative medicine 2011-01, Vol.2011 (2011), p.1-9
Hauptverfasser: de Gaspi, Fernanda Oliveira de G., Foglio, Mary Ann, de Carvalho, João Ernesto, Santos, Gláucia Maria T., Testa, Milene, Passarini, José Roberto, de Moraes, Cristiano Pedroso, Esquisatto, Marcelo A. Marreto, Mendonça, Josué S., Mendonça, Fernanda A. Sampaio
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Sprache:eng
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Zusammenfassung:This study evaluated the wound healing activity of hydroalcoholic leaf extract of Oncidium flexuosum Sims. (Orchidaceae), an important native plant of Brazil, combined or not with microcurrent stimulation. Wistar rats were randomly divided into four groups of nine animals: control (C), topical application of the extract (OF), treated with a microcurrent (10 μA/2 min) (MC), and topical application of the extract plus microcurrent (OF + MC). Tissue samples were obtained 2, 6, and 10 days after injury and submitted to structural and morphometric analysis. The simultaneous application of OF + MC was found to be highly effective in terms of the parameters analyzed (P
ISSN:1741-427X
1741-4288
DOI:10.1155/2011/950347