Low doses of 3-aminobenzamide, a poly(ADP-ribose) polymerase inhibitor, stimulate angiogenesis by regulating expression of urokinase type plasminogen activator and matrix metalloprotease 2

Poly(ADP-Ribose) polymerase (PARP) activity has been demonstrated fundamental in many cellular processes, including DNA repair, cell proliferation and differentiation. In particular, PARP activity has been recently found to affect proliferation, migration, and tube formation of human umbilical vein...

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Veröffentlicht in:	Vascular cell 2011-05, Vol.3 (1), p.12-12
Hauptverfasser:	Caldini, Riccardo, Fanti, Elena, Magnelli, Lucia, Barletta, Emanuela, Tanganelli, Elisabetta, Zampieri, Michele, Chevanne, Marta
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Binding sites Cancer Cell adhesion & migration Cell culture Colleges & universities Diabetic retinopathy DNA repair Drug therapy Enzyme inhibitors Enzymes Experiments Health aspects Neovascularization Rodents Vascular endothelial growth factor
Online-Zugang:	Volltext
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