Quantifying the impact of nonadherence patterns on exposure to oral immunosuppressants

Nonadherence to oral immunosuppressive drugs in renal transplant patients remains a major challenge. The objective of this study was to develop an adherence-exposure model that 1) quantifies the impact of nonadherence patterns on cyclosporine levels and 2) identifies nonadherence patterns that are a...

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Veröffentlicht in:	Therapeutics and clinical risk management 2011-01, Vol.7, p.149-156
Hauptverfasser:	Maclean, J Ross, Pfister, Marc, Zhou, Zexun, Roy, Amit, Tuomari, Vickie A, Heifets, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	cyclosporine Immunosuppressive agents kidney transplantation Kidney transplants logistic models Original Research Standard deviation Transplants & implants
Online-Zugang:	Volltext
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